POLR3F and WDR89

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR3F	WDR89
Description		RNA polymerase III subunit F	WD repeat domain 89
Image			No pdb structure
GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytoplasm Cytosol
	Molecular Function	DNA Binding Double-stranded DNA Binding DNA-directed RNA Polymerase Activity Protein Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Immune System Process Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Ventricular System Development Corpus Callosum Development
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		16 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 NINL PRP4K RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	5 interacting genes: APP PHYHIP POLR2M POLR3F SOCS6
Entrez ID		10621	112840
HPRD ID		15156	12635
Ensembl ID		ENSG00000132664	ENSG00000140006
Uniprot IDs		A0A8V8TL53 A0A8V8TMS0 Q05DB8 Q9H1D9	Q96FK6
PDB IDs		2DK5 2YU3 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III Transcription Factor TFIIIB Complex Transcription Initiation At RNA Polymerase III Promoter Transcription Preinitiation Complex Assembly TRNA Transcription DNA-templated Transcription Initiation RRNA Transcription Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Chromosome, Centromeric Region Protein-DNA Complex Assembly Histone H2AK5 Acetyltransferase Activity RNA Polymerase III Preinitiation Complex Assembly Negative Regulation Of Mast Cell Chemotaxis	Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway DNA-directed RNA Polymerase Complex Maintenance Of ER Location Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Endoplasmic Reticulum Localization Heparan Sulfate Binding Signaling Receptor Activator Activity Transcription Elongation Factor Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
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