TACC2 and HMG20B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TACC2	HMG20B
Description		transforming acidic coiled-coil containing protein 2	high mobility group 20B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane	Nucleus Nucleoplasm Chromosome Nuclear Body
	Molecular Function	Nuclear Receptor Binding	DNA Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Nuclear Migration Cerebral Cortex Development	Chromatin Organization Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways			HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia (time to first treatment) ( 33510140) Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)	Appendicular lean mass ( 33097823)
Interacting Genes		18 interacting genes: AURKC BORCS6 CLK2 CLVS2 CREBBP EP300 FMR1 FXR1 GRAMD4 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCA2 SMARCB1 TGM1 YEATS4	28 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 TUBB4A USHBP1 VIM WAC
Entrez ID		10579	10362
HPRD ID		05600	05703
Ensembl ID		ENSG00000138162	ENSG00000064961
Uniprot IDs		B2RWP4 B7ZMJ9 D6RAA5 E7EMZ9 E9PBC6 O95359 Q4VXL4 Q4VXL8	Q9P0W2
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Acetylation Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Acetyltransferase Activity Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Protein Acetylation Chromatin Organization Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Regulation Of DNA Repair Internal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Gluconeogenesis Transcription Coactivator Activity Acyltransferase Activity Regulation Of Cellular Response To Stress Negative Regulation Of Gluconeogenesis Histone H3K27 Acetyltransferase Activity Histone H3K9 Acetyltransferase Activity Positive Regulation Of Cell Differentiation Regulation Of Glucose Metabolic Process Positive Regulation Of Double-strand Break Repair Chromatin Remodeling Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Developmental Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Cell Development Regulation Of Multicellular Organismal Development Negative Regulation Of Small Molecule Metabolic Process Chromatin Binding Regulation Of DNA Metabolic Process RNA Strand Annealing Activity Positive Regulation Of DNA Repair Regulation Of Cell Development Protein Modification Process Regulation Of Double-strand Break Repair L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Nervous System Development Transcription Initiation-coupled Chromatin Remodeling Intracellular Membraneless Organelle Negative Regulation Of Centriole Replication Gluconeogenesis Kinetochore Positive Regulation Of Gene Expression, Epigenetic Hexose Biosynthetic Process DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process Regulation Of RNA Splicing
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