SLC34A2 and JAGN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC34A2	JAGN1
Description		solute carrier family 34 member 2	jagunal vesicle mediated transporter 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Membrane Apical Plasma Membrane Brush Border Membrane Vesicle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Sodium:phosphate Symporter Activity Protein Binding Symporter Activity Sodium Ion Binding Phosphate Ion Binding	Protein Binding
	Biological Process	In Utero Embryonic Development Monoatomic Ion Transport Sodium Ion Transport Phosphate Ion Transport Intracellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Response To Estrogen Sodium-dependent Phosphate Transport Transmembrane Transport	Immune System Process Neutrophil Mediated Immunity Exocytosis Endoplasmic Reticulum Organization Response To Glucose Protein Transport Vesicle-mediated Transport Insulin Secretion Neutrophil Differentiation Response To Endoplasmic Reticulum Stress Granulocyte Colony-stimulating Factor Signaling Pathway Defense Response To Fungus Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Insulin Metabolic Process Neutrophil Migration
Pathways		Type II Na+/Pi cotransporters Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) Surfactant metabolism Defective SLC34A2 causes PALM
Drugs
Diseases		Non-small cell lung cancer
GWAS		Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: AIG1 ERG28 FXYD6-FXYD2 GUCA2A JAGN1 LHFPL5 PLN PNLIPRP1 RTP2 SLC30A3 SLC35A1 SLC39A7 STRIT1 TEX264 TMEM128 TMEM239 TMEM42 TRARG1 TSPO2	128 interacting genes: AGPAT4 APP AQP6 ARL13B ARLN BCL2L13 BET1 BMP10 BNIP1 BNIP3 BSND BTNL9 CALHM6 CCL4L2 CD79A CDIPT CERS4 CGRRF1 CLDN7 CLEC12B CLEC4D CLEC7A CMTM5 COX20 CREB3L1 CYBC1 CYP4F2 DNAJC30 EBP EDA2R EHHADH ELOVL4 ERG28 ERGIC3 F11R FAM177A1 FAM209A FCGR1A FCRL2 FCRL4 FDFT1 FIS1 FKBP8 FNDC9 FRMD3 FXYD6 GIMAP1 GIMAP5 GJB5 GOLM1 GOSR2 GP2 GPR152 GPR37L1 HMOX1 HSD17B13 HTATIP2 ICMT IER3IP1 IFNGR2 IL3RA KASH5 KCNA1 KIR2DL3 KIR3DL3 LEMD1 LHFPL5 LMNA LPAR3 MFF MRM3 MTIF3 NINJ2 NRG1 OTULINL PDZK1IP1 PLP1 PLPP2 PSCA RETREG3 RTP2 SACM1L SAR1A SCD SEC22B SERP1 SLAMF6 SLC10A6 SLC16A2 SLC23A2 SLC34A2 SMAGP SMIM1 SMIM19 SSMEM1 STOML3 STX1A STX3 STX5 STX7 STX8 TECR TIMM23 TMEM100 TMEM106C TMEM120B TMEM128 TMEM14B TMEM207 TMEM237 TMEM242 TMEM243 TMEM52B TMEM65 TMIE TNFSF14 TREX1 TSNARE1 UBE2J1 USE1 VAMP2 VAMP5 VAPA VAPB VKORC1 VMA12 VSIG4 VTI1B
Entrez ID		10568	84522
HPRD ID		07251	13749
Ensembl ID		ENSG00000157765	ENSG00000171135
Uniprot IDs		O95436	Q8N5M9
PDB IDs			6WVD
Enriched GO Terms of Interacting Partners?		Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Membrane Response To Zinc Ion Endoplasmic Reticulum Membrane Regulation Of Cardiac Muscle Cell Contraction Circadian Sleep/wake Cycle, Sleep Regulation Of ATP-dependent Activity Phospholamban Complex Sarcoplasmic Reticulum Membrane Regulation Of Calcium Ion Import Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle CMP-N-acetylneuraminate Transmembrane Transporter Activity CMP-N-acetylneuraminate Transmembrane Transport 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction	Membrane Endoplasmic Reticulum Membrane SNAP Receptor Activity Endoplasmic Reticulum SNARE Complex Membrane Fusion Organelle Membrane Fusion SNARE Binding Protein Binding Vesicle Fusion Organelle Fusion Organelle Localization By Membrane Tethering Membrane Organization Golgi Vesicle Transport Membrane Docking Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endomembrane System Chloride Channel Inhibitor Activity Vesicle Docking Vesicle Organization Vesicle-mediated Transport Endoplasmic Reticulum Organization Plasma Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane External Side Of Plasma Membrane Establishment Of Protein Localization Cellular Localization Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex FFAT Motif Binding Lipid Biosynthetic Process Zymogen Granule Membrane Endoplasmic Reticulum-autophagosome Adaptor Activity Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Vesicle Positive Regulation Of Mitochondrial Fission Synaptic Vesicle COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization
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