DEAF1 and RIDA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DEAF1	RIDA
Description		DEAF1 transcription factor	reactive intermediate imine deaminase A
Image
GO Annotations	Cellular Component	Chromatin Fibrillar Center Extracellular Region Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Hydrolase Activity RNA Endonuclease Activity Producing 3'-phosphomonoesters, Hydrolytic Mechanism Deaminase Activity 2-iminobutanoate/2-iminopropanoate Deaminase 2-iminobutanoate Deaminase Activity 2-iminopropanoate Deaminase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Behavioral Fear Response Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Germ Cell Development Nervous System Development Visual Learning Anatomical Structure Morphogenesis Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Embryonic Skeletal System Development	MRNA Catabolic Process Lipid Metabolic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Translation L-threonine Catabolic Process To Glycine MRNA Destabilization Regulation Of Primary Metabolic Process
Pathways			Threonine catabolism
Drugs
Diseases
GWAS
Interacting Genes		24 interacting genes: AIMP2 ASCC2 CDC37 CDKN1A CDKN2A CEP76 FHL1 FXR1 FXR2 GOLGA3 GSK3A GSK3B HRAS INTS1 LMO4 PELI2 PIN1 PPP1CA PPP1CC RAD23B RIDA TK1 XRCC5 XRCC6	10 interacting genes: BANP DEAF1 HIVEP1 HPD MDM2 MT-CO2 SERPINA5 SPEN TMEM176A TRIB3
Entrez ID		10522	10247
HPRD ID		04027	03924
Ensembl ID		ENSG00000177030	ENSG00000132541
Uniprot IDs		A0A804HIS1 O75398	P52758
PDB IDs		2JW6 4A24 5UWW	1ONI
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Modification Process Cytosol Regulation Of Phosphorus Metabolic Process Cellular Response To Gamma Radiation Regulation Of Phosphorylation Oncogene-induced Cell Senescence Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Catalytic Activity Postsynapse Regulation Of Protein Phosphorylation Response To Gamma Radiation Positive Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Kinase Activity Regulation Of Metabolic Process Glycogen Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Macromolecule Metabolic Process Cellular Response To Ionizing Radiation Energy Reserve Metabolic Process Polysaccharide Metabolic Process Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus DNA End Binding Ku70:Ku80 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Cell Development Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of Protein Phosphorylation Presynapse Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Kinase Activity DNA-dependent Protein Kinase Complex Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Circadian Rhythm Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process	Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Repressor Complex Response To Formaldehyde Cellular Response To Vitamin B1 Protein C Inhibitor-coagulation Factor V Complex Protein C Inhibitor-TMPRSS7 Complex Protein C Inhibitor-PLAU Complex Protein C Inhibitor-TMPRSS11E Complex Protein C Inhibitor-coagulation Factor Xa Complex Protein C Inhibitor-KLK3 Complex Protein C Inhibitor-plasma Kallikrein Complex Protein C Inhibitor-thrombin Complex Protein C Inhibitor-coagulation Factor XI Complex Protein C Inhibitor-PLAT Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Body 4-hydroxyphenylpyruvate Dioxygenase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Seminal Clot Liquefaction Response To Vitamin B1 Response To Water-immersion Restraint Stress Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Actinomycin D Platelet Dense Tubular Network Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen NEDD8 Ligase Activity Response To Actinomycin D Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Positive Regulation Of Proteasomal Protein Catabolic Process Acrosin Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To UV-C Ubiquitin-protein Transferase Regulator Activity
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