SEC23B and RIN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEC23B	RIN1
Description		SEC23 homolog B, COPII component	Ras and Rab interactor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Endocytic Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport COPII-coated Vesicle Cargo Loading COPII-coated Vesicle Budding	Endocytosis Signal Transduction Vesicle-mediated Transport Intracellular Signal Transduction
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Congenital dyserythropoietic anemias (CDAs)
GWAS		Refractive error ( 32231278)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		27 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 RIN1 SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UBA52 UBC UGT1A1	49 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP ITSN1 KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1
Entrez ID		10483	9610
HPRD ID		11543	05813
Ensembl ID		ENSG00000101310	ENSG00000174791
Uniprot IDs		A0A2R8YFH5 Q15437	A0A0S2Z4T5 A0A0S2Z4U0 Q13671
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Vesicle Cargo Loading Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Vesicle Transport COPII-coated ER To Golgi Transport Vesicle ER To Golgi Transport Vesicle Membrane Protein Modification Process Transport Vesicle Vesicle Coating Protein Ubiquitination Golgi Organization Maintenance Of Protein Localization In Organelle Cis-Golgi Network Endoplasmic Reticulum Protein Modification By Small Protein Conjugation Maintenance Of Protein Location In Cell Maintenance Of Protein Location Intracellular Protein Transport Maintenance Of Location In Cell COPI-coated Vesicle Post-translational Protein Modification Protein Tag Activity Maintenance Of Location COPII Vesicle Coat COPI-coated Vesicle Membrane Vesicle-mediated Transport Zymogen Granule Membrane Trans-Golgi Network Transport Vesicle COPII-coated Vesicle Cargo Loading Golgi Membrane In Utero Embryonic Development Chordate Embryonic Development COPII Vesicle Coating Golgi Apparatus Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Viral Protein Processing Endoplasmic Reticulum Exit Site Positive Regulation Of Viral Genome Replication Protein Transport Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Metabolic Process	Cytosol Cytoplasm Perinuclear Region Of Cytoplasm Phosphoserine Residue Binding Epidermal Growth Factor Receptor Signaling Pathway Regulation Of MAPK Cascade ERBB Signaling Pathway GDP Binding Intracellular Signaling Cassette MAPK Cascade Identical Protein Binding Regulation Of Intracellular Signal Transduction Protein Sequestering Activity ERBB3:ERBB2 Complex Regulation Of Autophagy Melanosome Positive Regulation Of Intracellular Signal Transduction Cellular Localization Vesicle-mediated Transport Schwann Cell Development Protein Tyrosine Kinase Activity Glial Cell Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB2 Signaling Pathway Positive Regulation Of MAPK Cascade Establishment Of Protein Localization Positive Regulation Of Establishment Of T Cell Polarity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Binding Establishment Of Localization In Cell Regulation Of Cell Communication Signal Transduction Regulation Of Signaling ErbB-3 Class Receptor Binding Regulation Of Cellular Component Organization Intracellular Transport Regulation Of Actin Filament-based Process Protein Binding Regulation Of Establishment Of T Cell Polarity Regulation Of Signal Transduction Protein Modification Process Regulation Of Fibroblast Proliferation Regulation Of ERK1 And ERK2 Cascade Protein Phosphatase Binding Myelination Axon Ensheathment Regulation Of Protein Localization Negative Regulation Of Signaling Negative Regulation Of Cell Communication ERBB2-EGFR Signaling Pathway
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