CEACAM5 and DISP3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		CEACAM5	DISP3
Description		CEA cell adhesion molecule 5	dispatched RND transporter family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Extracellular Exosome Side Of Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Nuclear Membrane
	Molecular Function	Protein Binding GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Apoptotic Process Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis	Lipid Metabolic Process Smoothened Signaling Pathway Steroid Metabolic Process Cholesterol Metabolic Process Cell Differentiation Regulation Of Lipid Transport Cholesterol Homeostasis Negative Regulation Of Neuron Differentiation Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Cell surface interactions at the vascular wall
Drugs		Labetuzumab S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		7 interacting genes: CEACAM1 CEACAM6 DISP3 EWSR1 HNRNPM IMPDH2 UQCC2	5 interacting genes: CA2 CEACAM5 MTNR1B MYCBP RASGRP2
Entrez ID		1048	57540
HPRD ID		00274	13852
Ensembl ID		ENSG00000105388	ENSG00000204624
Uniprot IDs		A0A024R0K5 P06731 Q53G30	Q9P2K9
PDB IDs		1E07 2QSQ 2QST 2VER 8BW0
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Dipeptide Transmembrane Transport Cyanamide Hydratase Activity Arylesterase Activity Positive Regulation Of Cellular PH Reduction Regulation Of Chloride Transport Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep GPI Anchor Binding Regulation Of Monoatomic Anion Transport Carbonate Dehydratase Activity Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Diacylglycerol Binding Carbon Dioxide Transport Positive Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of Cytosolic Calcium Ion Concentration Angiotensin-activated Signaling Pathway Negative Regulation Of Myotube Differentiation Negative Regulation Of Anoikis Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle One-carbon Compound Transport Regulation Of Anoikis GTPase Regulator Activity
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