TIMM44 and SFT2D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TIMM44	SFT2D2
Description		translocase of inner mitochondrial membrane 44	SFT2 domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Membrane	Cytoplasm Endomembrane System Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Protein-folding Chaperone Binding	Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix Establishment Of Protein Localization	Protein Transport Vesicle-mediated Transport
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS			Alzheimer's disease ( 30636644) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		8 interacting genes: ARAF CCDC57 CMTM5 PRPF6 SFT2D2 TIMM17A UBASH3A UBQLN2	29 interacting genes: AQP6 ATP5PF BNIP2 CREB3 ELOVL4 GPR152 HIBADH HSD17B11 HSD17B13 IFNGR2 INPP5K LMNA MOB2 NDRG4 PBX3 PLIN2 PLIN3 REEP2 REEP4 SLC10A1 SLC10A6 SLC30A8 STOM TAS2R5 TCP11X2 TIMM44 TMEM143 TMEM14B TMEM51
Entrez ID		10469	375035
HPRD ID		05450	14192
Ensembl ID		ENSG00000104980	ENSG00000213064
Uniprot IDs		O43615	O95562
PDB IDs		2CW9
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Triglyceride Storage Steroid Dehydrogenase Activity Lipid Droplet Bile Acid:sodium Symporter Activity Lipid Droplet Disassembly Endoplasmic Reticulum Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Membrane Positive Regulation Of Lipid Storage Bile Acid And Bile Salt Transport Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nuclear Envelope Organization
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