CNPY2 and MLXIP

Number of citations of the paper that reports this interaction (PubMedID 12826659)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		CNPY2	MLXIP
Description		canopy FGF signaling regulator 2	MLX interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum	Chromatin Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Height ( 31562340 34270706) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 26785701)	A body shape index ( 34021172) Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Body mass index ( 29273807) Diastolic blood pressure ( 30224653) Gout ( 32238385 33832965) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		5 interacting genes: ADRA2C APP MLXIP MYLIP RAB27B	3 interacting genes: CNPY2 MLX YWHAB
Entrez ID		10330	22877
HPRD ID		12056	10478
Ensembl ID		ENSG00000257727	ENSG00000175727
Uniprot IDs		Q9Y2B0	Q9HAP2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuron Differentiation Alpha-2A Adrenergic Receptor Binding Endosome Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Epinephrine Secretion Regulation Of Neuron Differentiation Negative Regulation Of Protein Localization Alpha2-adrenergic Receptor Activity Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Axo-dendritic Transport Intermediate-density Lipoprotein Particle Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Microtubule-based Transport Transport Along Microtubule Amylin Binding Positive Regulation Of Protein Catabolic Process Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Platelet Dense Granule Membrane Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Axon Choice Point Recognition Regulation Of Blood Circulation
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