B3GALT5 and ABCG1

		B3GALT5	ABCG1
Description		beta-1,3-galactosyltransferase 5	ATP binding cassette subfamily G member 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Membrane	Golgi Membrane Nucleoplasm Mitochondrion Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Membrane Recycling Endosome
	Molecular Function	Protein Binding N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity	Nucleotide Binding Protein Binding ATP Binding Phospholipid Binding Cholesterol Binding ATP Hydrolysis Activity Toxin Transmembrane Transporter Activity ABC-type Sterol Transporter Activity Protein Homodimerization Activity ADP Binding Protein Heterodimerization Activity Protein Dimerization Activity Phosphatidylcholine Floppase Activity Cholesterol Transfer Activity Floppase Activity ABC-type Transporter Activity
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation Lipid Metabolic Process Oligosaccharide Biosynthetic Process Response To Bacterium Carbohydrate Derivative Biosynthetic Process	Lipid Transport Cholesterol Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Efflux Negative Regulation Of Cholesterol Storage Negative Regulation Of Lipid Storage Cholesterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Phospholipid Efflux Response To Lipid Lipid Translocation Low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Remodeling Glycoprotein Transport Cholesterol Homeostasis Amyloid Precursor Protein Catabolic Process Reverse Cholesterol Transport Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Protein Secretion Transmembrane Transport Phospholipid Homeostasis Cellular Response To High Density Lipoprotein Particle Stimulus Regulation Of Cholesterol Metabolic Process Positive Regulation Of Amyloid-beta Formation Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Lewis blood group biosynthesis	ABC transporters in lipid homeostasis HDL remodeling NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs			ATP
Diseases
GWAS		Alcohol dependence ( 26365420) Corneal astigmatism ( 29422769) Metabolite levels ( 23823483) Obsessive-compulsive symptoms ( 26859814) Suicide risk ( 21041247)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Eating disorder in bipolar disorder ( 26433762) Gout ( 22179738) HDL cholesterol levels ( 32203549) Idiopathic osteonecrosis of the femoral head ( 28000841) Neuritic plaque ( 25188341)
Interacting Genes		6 interacting genes: ABCG1 CLEC2D DEFB103A DEFB103B RRP1 RRP1B	4 interacting genes: ABCG4 AQP6 B3GALT5 PTPRF
Entrez ID		10317	9619
HPRD ID		06818	04355
Ensembl ID		ENSG00000183778	ENSG00000160179
Uniprot IDs		A0A0A0MS93 Q9Y2C3	P45844
PDB IDs			7FDV 7OZ1 7R8C 7R8D 7R8E
Enriched GO Terms of Interacting Partners?		CCR6 Chemokine Receptor Binding Preribosome, Small Subunit Precursor Chemoattractant Activity Killing By Host Of Symbiont Cells Biological Process Involved In Interaction With Symbiont Positive Chemotaxis Defense Response To Gram-negative Bacterium ABC-type Sterol Transporter Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Golgi Lumen Killing Of Cells Of Another Organism Defense Response To Gram-positive Bacterium Glycoprotein Transport Cellular Response To High Density Lipoprotein Particle Stimulus Antimicrobial Humoral Response Floppase Activity Cell Killing RRNA Processing Phosphatidylcholine Floppase Activity Cell Chemotaxis Toxin Transmembrane Transporter Activity Granular Component RRNA Metabolic Process Humoral Immune Response Negative Regulation Of Cholesterol Storage Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Xenobiotic Export From Cell Low-density Lipoprotein Particle Remodeling Phospholipid Homeostasis Phospholipid Efflux Amyloid Precursor Protein Catabolic Process Reverse Cholesterol Transport External Side Of Plasma Membrane Negative Regulation Of Macrophage Derived Foam Cell Differentiation Response To Other Organism Negative Regulation Of GTPase Activity Locomotion Defense Response To Bacterium Chemotaxis Host-mediated Activation Of Viral Transcription Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Amyloid-beta Formation Negative Regulation Of Lipid Storage Intracellular Cholesterol Transport High-density Lipoprotein Particle Remodeling Response To External Biotic Stimulus Response To Bacterium Intracellular Sterol Transport Cholesterol Transfer Activity Amyloid Precursor Protein Metabolic Process	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Chondroitin Sulfate Proteoglycan Binding ABC-type Sterol Transporter Activity Cytoplasmic Vesicle Membrane Cellular Response To High Density Lipoprotein Particle Stimulus Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Negative Regulation Of Receptor Binding Monoatomic Anion Channel Activity Renal Water Transport Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Ammonium Transmembrane Transport Ammonium Channel Activity N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Water Channel Activity Carbon Dioxide Transport One-carbon Compound Transport Water Transport Negative Regulation Of Protein Binding Regulation Of Neuron Projection Regeneration Neuron Projection Regeneration Regulation Of Axon Regeneration Transmembrane Receptor Protein Tyrosine Phosphatase Activity Peptidyl-tyrosine Dephosphorylation Synaptic Membrane Adhesion Hexosyltransferase Activity Oligosaccharide Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Efflux Cholesterol Efflux Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Metabolic Process Fluid Transport Positive Regulation Of Steroid Biosynthetic Process Positive Regulation Of Cholesterol Transport Cellular Response To Lipoprotein Particle Stimulus Channel Activity ABC-type Transporter Activity Positive Regulation Of Steroid Metabolic Process Regulation Of Protein Binding Regulation Of Cholesterol Efflux Regulation Of Cholesterol Metabolic Process
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