BCAS2 and TRNAU1AP

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		BCAS2	TRNAU1AP
Description		BCAS2 pre-mRNA processing factor	tRNA selenocysteine 1 associated protein 1
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Centrosome Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding	TRNA Binding Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Ovarian Follicle Development MRNA Processing RNA Splicing Protein Catabolic Process Oogenesis Oocyte Development Spindle Assembly	Selenocysteine Incorporation Translation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autism ( 24189344) Chronotype ( 30696823)
Interacting Genes		82 interacting genes: ACY1 AIMP2 ANKHD1 BLK CCDC120 CCDC17 CNOT4 CPSF7 DMRTB1 DUT ECM1 EIF4ENIF1 EMILIN3 ENKD1 EP300 ESR1 ESR2 FAM86C1P FHIT GOLGA2 HGS HNRNPLL HSF2BP IFI35 IKZF3 KRT20 KRT27 KRT31 KRT34 KRT35 KRT36 KRT37 KRT75 KRTAP19-6 KRTAP8-1 LARP4 LMO1 LMO2 LMO3 LMO4 MBNL1 MED29 MIIP MYOZ3 NIP7 OIP5 PAX5 PCBD2 PFDN5 PGR PLAGL2 PLEKHF2 POT1 PPARG PRRC2B QKI RBM22 RBPMS RPL5 SAXO4 SF1 SLAIN1 SMARCD1 SNRNP200 SNRPC SNW1 SPMIP5 SPMIP6 TCF4 TCHP TFIP11 TP53BP2 TRAF1 TRNAU1AP TXN2 TXNRD2 UBC USHBP1 WDR83 YPEL3 ZMAT5 ZWINT	9 interacting genes: BCAS2 DMRTB1 GTSE1 PRPF39 PRRC2B QKI RBM42 SECISBP2 USP10
Entrez ID		10286	54952
HPRD ID		05777	18035
Ensembl ID		ENSG00000116752	ENSG00000180098
Uniprot IDs		B2R7W3 O75934	Q9NX07
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7W59 7W5A 7W5B 8C6J 8CH6 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD	2DHG 2DIV
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Binding Nucleic Acid Binding MRNA Metabolic Process MRNA Processing Structural Molecule Activity Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Estrogen Response Element Binding RNA Binding RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Binding RNA Processing Catalytic Step 2 Spliceosome Nucleus Positive Regulation Of Biosynthetic Process Transcription Coactivator Activity Nuclear Receptor Activity Nuclear Estrogen Receptor Activity TFIIB-class Transcription Factor Binding Nuclear Receptor-mediated Signaling Pathway Epithelial Cell Differentiation Nuclear Steroid Receptor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Morphogenesis Of An Epithelium MRNA Binding DNA-binding Transcription Factor Binding Regulation Of RNA Splicing Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Protein-containing Complex Organization Steroid Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Cell Differentiation Supramolecular Fiber Organization Hormone-mediated Signaling Pathway Tissue Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization	RNA Splicing Negative Regulation Of MRNA Metabolic Process MRNA Processing Stress Granule Assembly Nucleic Acid Metabolic Process RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Splicing, Via Spliceosome DNA Damage Response, Signal Transduction By P53 Class Mediator Membraneless Organelle Assembly RNA Metabolic Process Translational Elongation RNA Binding Regulation Of MRNA Metabolic Process MRNA Stabilization Internal N(7)-methylguanine-containing RNA Reader Activity Nucleobase-containing Compound Metabolic Process RNA Processing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Stress Granule Assembly Myofibroblast Contraction Negative Regulation Of RNA Catabolic Process Negative Regulation Of MiRNA Catabolic Process Signal Transduction By P53 Class Mediator Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA 3'-UTR Binding Spliceosome-depend Formation Of Circular RNA Pre-mRNA 5'-splice Site Binding Selenocysteine Insertion Sequence Binding Commitment Complex Signal Transduction In Response To DNA Damage Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of RNA Splicing Regulation Of MRNA Stability Germ Cell Development Microglia Differentiation Negative Regulation Of Macrophage Differentiation Spliceosomal Complex MRNA 5'-splice Site Recognition Selenocysteine Incorporation Monoubiquitinated Protein Deubiquitination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Organelle Assembly Regulation Of RNA Stability Regulation Of Stress Granule Assembly Intracellular MRNA Localization
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