GLYAT and ZDHHC5

		GLYAT	ZDHHC5
Description		glycine-N-acyltransferase	zDHHC palmitoyltransferase 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Golgi Membrane Nucleoplasm Plasma Membrane Membrane Dendrite Synapse Phagocytic Vesicle Postsynapse Glutamatergic Synapse GABA-ergic Synapse Postsynaptic Specialization, Intracellular Component
	Molecular Function	Protein Binding Transferase Activity Acyltransferase Activity Glycine N-acyltransferase Activity Glycine N-benzoyltransferase Activity	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Glycine Metabolic Process Acyl-CoA Metabolic Process Xenobiotic Metabolic Process Response To Toxic Substance Monocarboxylic Acid Metabolic Process Benzoyl-CoA Metabolic Process	Immune System Process Lipid Transport Fatty Acid Transport Protein Palmitoylation Protein Catabolic Process Response To Muramyl Dipeptide Defense Response To Bacterium NLRP3 Inflammasome Complex Assembly Innate Immune Response Protein Maturation Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Protein K63-linked Ubiquitination Protein Localization To Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Pyroptotic Inflammatory Response Pyroptotic Cell Death Positive Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Phagocytic Vesicle
Pathways		Conjugation of salicylate with glycine Conjugation of benzoate with glycine Aspirin ADME	Maturation of spike protein
Drugs		Glycine
Diseases
GWAS		Body mass (lean) ( 23108985) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Diastolic blood pressure ( 27841878) Heel bone mineral density x serum urate levels interaction ( 34046847) Hepcidin/ferritin ratio ( 27846281) Monocyte count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)	Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Schizophrenia ( 25056061 28991256 29483656) Sociability score ( 34054130) Worry too long after an embarrassing experience ( 34054130)
Interacting Genes		10 interacting genes: CYSRT1 GPRASP1 KRTAP1-1 KRTAP1-3 KRTAP10-8 NBPF19 NOTCH2NLA PTN RBM48 ZDHHC5	5 interacting genes: DTX4 FAM111A GLYAT MS4A6A SRPK2
Entrez ID		10249	25921
HPRD ID		07603	15720
Ensembl ID		ENSG00000149124	ENSG00000156599
Uniprot IDs		A0A384P5E3 Q6IB77	Q9C0B5
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament	Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Negative Regulation Of Viral Genome Replication Benzoyl-CoA Metabolic Process Glycine N-benzoyltransferase Activity Regulation Of Viral Life Cycle Regulation Of Viral Process Glycine N-acyltransferase Activity Nuclear Speck Organization
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