MPHOSPH10 and PCYOX1

		MPHOSPH10	PCYOX1
Description		M-phase phosphoprotein 10	prenylcysteine oxidase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex	Lysosome Very-low-density Lipoprotein Particle Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	Prenylcysteine Oxidase Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Oxygen As Acceptor FAD Binding Farnesylcysteine Lyase Activity
	Biological Process	RNA Splicing, Via Transesterification Reactions RRNA Processing RNA Processing RNA Splicing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis	Prenylated Protein Catabolic Process Prenylcysteine Catabolic Process
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Metabolite levels ( 23823483)	Acne (severe) ( 24927181) Chronotype ( 30696823) Liver enzyme levels (alkaline phosphatase) ( 33972514) Male-pattern baldness ( 28196072) Morning person ( 30696823)
Interacting Genes		11 interacting genes: C2orf78 CSNK2A1 E2F1 GSTP1 IMP3 IMP4 NEUROG1 PCYOX1 PPEF2 PPP1CA RNF10	4 interacting genes: CYP26B1 HOXA1 MPHOSPH10 OGT
Entrez ID		10199	51449
HPRD ID		10404	11422
Ensembl ID		ENSG00000124383	ENSG00000116005
Uniprot IDs		O00566	Q9UHG3
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Preribosome Mpp10 Complex Regulation Of Apoptotic Signaling Pathway SnoRNA Binding Protein Serine/threonine Kinase Inhibitor Activity Negative Regulation Of Apoptotic Signaling Pathway Double-strand Break Repair Via Nonhomologous End Joining Hsp90 Protein Binding Regulation Of Glial Cell Proliferation Dinitrosyl-iron Complex Binding S-nitrosoglutathione Binding Nitric Oxide Storage Prenylcysteine Oxidase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Oxygen As Acceptor Prenylcysteine Catabolic Process Farnesylcysteine Lyase Activity RRNA Binding Maturation Of SSU-rRNA Regulation Of Translational Initiation Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Protein Kinase CK2 Complex RNA Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Phase Transition DNA Damage Checkpoint Signaling Forebrain Development Regulation Of Gliogenesis Regulation Of Fibroblast Proliferation Lens Fiber Cell Apoptotic Process TRAF2-GSTP1 Complex Glutathione Derivative Biosynthetic Process Cellular Response To Cell-matrix Adhesion Learned Vocalization Behavior Hard Palate Morphogenesis Mastication Vestibulocochlear Nerve Formation Positive Regulation Of Exit From Mitosis Negative Regulation Of Saliva Secretion Iron Ion Binding Protein Serine/threonine Phosphatase Activity Protein Dephosphorylation Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Prenylated Protein Catabolic Process Small-subunit Processome Ribosomal Small Subunit Biogenesis	Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Response To Nutrient All-trans Retinoic Acid 18-hydroxylase Activity Positive Regulation Of Tongue Muscle Cell Differentiation Retinoic Acid Catabolic Process Protein O-acetylglucosaminyltransferase Activity Mpp10 Complex Positive Regulation Of Skeletal Muscle Fiber Differentiation Outer Ear Morphogenesis Embryonic Neurocranium Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Regulation Of Transcription By Glucose Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Sno(s)RNA-containing Ribonucleoprotein Complex Tongue Morphogenesis Retinoic Acid 4-hydroxylase Activity Cornification Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Skeletal Muscle Fiber Differentiation Establishment Of T Cell Polarity NSL Complex Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Response To Vitamin A Positive Regulation Of Myotube Differentiation Regulation Of Retinoic Acid Receptor Signaling Pathway Embryonic Morphogenesis Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Acetylglucosaminyltransferase Activity Response To Nutrient Levels Retinoic Acid Binding Sin3-type Complex Regulation Of Skeletal Muscle Cell Differentiation Retinoic Acid Receptor Signaling Pathway Histone Acetyltransferase Complex Inflammatory Response Cochlea Morphogenesis Regulation Of Protein Localization To Synapse Negative Regulation Of Stem Cell Population Maintenance Retinoic Acid Metabolic Process Proximal/distal Pattern Formation Vitamin Metabolic Process
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