LHFPL2 and SCARF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LHFPL2	SCARF1
Description		LHFPL tetraspan subfamily member 2	scavenger receptor class F member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Platelet Alpha Granule Membrane	Plasma Membrane Membrane Endocytic Vesicle Membrane
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding
	Biological Process	Single Fertilization Development Of Primary Female Sexual Characteristics Development Of Primary Male Sexual Characteristics Positive Regulation Of Fertilization	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration
Pathways		Platelet degranulation	Scavenging by Class F Receptors Scavenging by Class F Receptors
Drugs
Diseases
GWAS		Birth weight ( 31043758) Blood and toenail selenium levels ( 25343990) Hippocampal atrophy ( 19668339) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease (familial, age at onset) ( 27402877) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 30578418 28135244 27841878) Systolic blood pressure ( 30578418 27841878)	Blood protein levels ( 30072576) Intracranial aneurysm ( 30823506) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: FXYD6 GAST GJA5 GJB1 GPR152 OLFM4 SCARF1 SNORC TBCA TMEM128 TMEM147	22 interacting genes: CALR CLDN7 COQ9 CREB3L1 CYSRT1 FAM209A GJA8 GPR37L1 GPX8 HSD17B13 KCNJ6 KRTAP1-1 KRTAP10-8 KRTAP5-7 LCE1D LHFPL2 MEOX2 MRM3 NEMP1 SCARF2 SLC7A14 TGM1
Entrez ID		10184	8578
HPRD ID		17272	06386
Ensembl ID		ENSG00000145685	ENSG00000074660
Uniprot IDs		Q6ZUX7	A8K6Z5 Q14162
PDB IDs			8HN0 8HNA
Enriched GO Terms of Interacting Partners?		Gap Junction Assembly Gap Junction Channel Activity Connexin Complex Gap Junction Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Renin Secretion Into Blood Stream Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Regulation Of AV Node Cell Action Potential Protein Localization To Nuclear Inner Membrane Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Cell-cell Junction Assembly Gap Junction Hemi-channel Activity Connexin Binding Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential SA Node Cell Action Potential Atrioventricular Valve Development AV Node Cell To Bundle Of His Cell Communication Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Membrane Depolarization During Action Potential Post-chaperonin Tubulin Folding Pathway Ion Channel Regulator Activity Cell-cell Junction Organization Atrial Septum Development Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Potassium Ion Transport Cholesterol Catabolic Process Positive Regulation Of Axon Regeneration	Cornified Envelope
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