CTDSP2 and CDCA3

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CTDSP2	CDCA3
Description		CTD small phosphatase 2	cell division cycle associated 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Cytosol Adherens Junction
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Hydrolase Activity Phosphatase Activity Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Protein Ubiquitination Cell Division
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Height ( 31562340) Hematocrit ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278) Trochanter size ( 31053729)
Interacting Genes		14 interacting genes: AKT1 AR CDCA3 CDK4 CSF1R EPHA1 EPHA3 INSRR LCN2 N4BP3 POLR2A PTK7 SNAI1 TYRO3	10 interacting genes: APP BCL11A CTDSP1 CTDSP2 CUL1 SKP1 TRAF1 TRAF2 UBC WEE1
Entrez ID		10106	83461
HPRD ID		12281	09670
Ensembl ID		ENSG00000175215	ENSG00000111665
Uniprot IDs		O14595	F5GX58 F8WDL1 J3KMY0 Q99618
PDB IDs		2Q5E
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Tyrosine Kinase Activity Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Response To Lipid ATP Binding Receptor Complex Transferase Activity Response To Lipid Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Cell Migration Cellular Response To Ether Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Migration Male Sex Determination Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Positive Regulation Of Cell Motility Kinase Binding Positive Regulation Of Locomotion Phosphatidylinositol 3-kinase Binding Cell Motility Regulation Of Protein Localization To Plasma Membrane Protein Autophosphorylation Protein Phosphorylation Response To Ether Negative Regulation Of Toll-like Receptor Signaling Pathway Sex Determination Positive Regulation Of Cellular Component Organization Positive Regulation Of Cell Projection Organization Nucleotide Binding Phosphorylation Regulation Of Cellular Component Organization Regulation Of Protein Localization To Cell Periphery Tissue Morphogenesis Cellular Response To Cytokine Stimulus Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Regulation Of Protein Localization To Membrane Positive Regulation Of Morphogenesis Of An Epithelium Regulation Of Toll-like Receptor Signaling Pathway Developmental Process Involved In Reproduction Regulation Of Apoptotic Process Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor	Protein Modification Process Ubiquitin Ligase Complex Scaffold Activity Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Thioesterase Binding Protein Metabolic Process Protein Modification By Small Protein Conjugation Ubiquitin Protein Ligase Binding Post-translational Protein Modification Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Programmed Cell Death Molecular Function Activator Activity Cell Death Positive Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Tumor Necrosis Factor Receptor Binding Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Mitotic Cell Cycle Nucleoplasm Negative Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Epithelial Cell Apoptotic Process Protein Monoubiquitination Protein Polyubiquitination SCF Ubiquitin Ligase Complex SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Tumor Necrosis Factor-mediated Signaling Pathway TORC2 Complex Disassembly Negative Regulation Of Cell Cycle Process Negative Regulation Of Branching Morphogenesis Of A Nerve Negative Regulation Of Neuron Remodeling TORC1 Signaling Regulation Of Apoptotic Process Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Phosphatase Activity
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