PCAT1 and PCCB

Number of citations of the paper that reports this interaction (PubMedID 31903119)
55

Data Source:
BioGRID (unspecified method)

		PCAT1	PCCB
Description		prostate cancer associated transcript 1	propionyl-CoA carboxylase subunit beta
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Matrix Cytosol Catalytic Complex
	Molecular Function		Nucleotide Binding Propionyl-CoA Carboxylase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process		Fatty Acid Metabolic Process Fatty Acid Catabolic Process Branched-chain Amino Acid Metabolic Process Short-chain Fatty Acid Catabolic Process
Pathways			Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Propionyl-CoA catabolism Mitochondrial protein degradation
Drugs			Biotin Valine
Diseases			Propionic acidemia
GWAS		Body mass index ( 25673413) Heel bone mineral density ( 28869591 30598549) Intracranial aneurysm ( 29531279) Lung cancer in never smokers ( 28604730)	A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Coronary artery disease ( 33020668) Fibrinogen ( 20031576 23969696) Fibrinogen levels ( 28107422) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Height ( 20881960 28552196) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Metabolic syndrome ( 31589552) Non-word reading ( 30741946) Schizophrenia ( 25056061 28991256 29483656) Serum alkaline phosphatase levels ( 33339817 33547301) Systolic blood pressure ( 30224653) Total bilirubin levels ( 29403010) Triglyceride levels ( 32154731 32203549) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Walking pace ( 33128006)
Interacting Genes		13 interacting genes: AAMP CASD1 FAF2 FILNC1 GJA10 GRWD1 HNRNPH1 NAV3 PCCB PCLO PDIA3 RPL11 TUFM	9 interacting genes: ACTN3 DSCR9 EPHB1 FBXL17 FXR1 H19 MTDH PCAT1 PCCA
Entrez ID		100750225	5096
HPRD ID			01982
Ensembl ID		ENSG00000253438	ENSG00000114054
Uniprot IDs			P05166
PDB IDs			7YBU 8XL3 8XL4 8XL5
Enriched GO Terms of Interacting Partners?
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