USP2-AS1 and DCAF13

Number of citations of the paper that reports this interaction (PubMedID 36359803)
47

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		USP2-AS1	DCAF13
Description		USP2 antisense RNA 1	DDB1 and CUL4 associated factor 13
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Cell Junction Small-subunit Processome Cul4-RING E3 Ubiquitin Ligase Complex Ribonucleoprotein Complex
	Molecular Function		RNA Binding Protein Binding Nuclear Estrogen Receptor Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process		Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Oocyte Growth RRNA Processing Spindle Assembly Involved In Female Meiosis Female Gamete Generation Protein Ubiquitination Ribosome Biogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Epigenetic Programming In The Zygotic Pronuclei Decidualization Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Neddylation
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Parental longevity (both parents in top 10%) ( 29227965)
Interacting Genes		15 interacting genes: ARIH2 ATR COX15 CTSC DCAF13 ENO2 FAAH2 PCBD2 PEX2 PUS1 RPSA SPRR4 STX10 TP53I3 TSC1	5 interacting genes: PABPC1 PTEN TK1 USP2-AS1 WARS1
Entrez ID		100499227	25879
HPRD ID			08528
Ensembl ID		ENSG00000245248	ENSG00000164934
Uniprot IDs			A0A087WT20 Q9NV06
PDB IDs			7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Negative Regulation Of Phosphorylation Negative Regulation Of Protein Phosphorylation Rhythmic Synaptic Transmission Negative Regulation Of Phosphate Metabolic Process Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity DNA Synthesis Involved In Mitotic DNA Replication Thymidine Kinase Activity Tryptophan-tRNA Ligase Activity Tryptophanyl-tRNA Aminoacylation Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Thymidine Biosynthetic Process MCRD-mediated MRNA Stability Complex Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Density Assembly Thymidine Metabolic Process Kinase Inhibitor Activity Locomotor Rhythm Phosphatidylinositol-3-phosphate Phosphatase Activity Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Postsynaptic Specialization Assembly Prepulse Inhibition Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Maternal Behavior Presynaptic Membrane Organization Schmidt-Lanterman Incisure Anaphase-promoting Complex Binding Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Pyrimidine Nucleoside Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Translation Activator Activity Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
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