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PJA2

Description praja ring finger ubiquitin ligase 2
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Cytoplasm
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Postsynaptic Density
  • Intermediate Filament Cytoskeleton
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Protein Kinase A Catalytic Subunit Binding
  • Protein Kinase A Regulatory Subunit Binding
  • Metal Ion Binding
Biological Process
  • Inflammatory Response
  • Long-term Memory
  • Regulation Of Protein Kinase A Signaling
  • Protein Ubiquitination
  • Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
  • Hippo Signaling
  • Regulation Of Macrophage Activation
  • Innate Immune Response
  • Positive Regulation Of JNK Cascade
  • Positive Regulation Of P38MAPK Cascade
Pathways
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Body mass index ( 29273807)
  • Frontotemporal dementia with GRN mutation ( 29724592)
  • HDL cholesterol levels ( 32203549)
  • Heel bone mineral density ( 30598549)
Interacting Genes 14 interacting genes: KSR1 MAGED1 MFHAS1 MOB1A PRKAR1A PRKAR2A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2J1 UBE2L6 UBE2N UBE2W
Entrez ID 9867
HPRD ID 11436
Ensembl ID ENSG00000198961
Uniprot IDs O43164
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025