EEF1E1

Description		eukaryotic translation elongation factor 1 epsilon 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	Protein Binding
	Biological Process	Translation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To Leukemia Inhibitory Factor Positive Regulation Of Cellular Senescence Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Refractive error ( 32231278) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Novel Interacting Genes		7 novel interacting genes: ATM ATR CALCOCO2 CDC42 CEBPA FNDC3B NAT9
Interacting Genes		7 interacting genes: ATM ATR CALCOCO2 CDC42 CEBPA FNDC3B NAT9
Entrez ID		9521
HPRD ID		10931
Ensembl ID		ENSG00000124802
Uniprot IDs		O43324
PDB IDs		2UZ8 4BL7 4BVX 4BVY 5BMU 5Y6L
Enriched GO Terms of Interacting Partners?		Establishment Of RNA Localization To Telomere Establishment Of Protein-containing Complex Localization To Telomere Positive Regulation Of Telomerase Catalytic Core Complex Assembly Histone H2AXS139 Kinase Activity DNA Strand Resection Involved In Replication Fork Processing Replicative Senescence Regulation Of Cellular Response To Heat Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Organelle Organization Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Site Of Double-strand Break Cellular Response To Gamma Radiation Positive Regulation Of Signal Transduction By P53 Class Mediator Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Macrophage Differentiation Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Gamma Radiation Mitotic G2/M Transition Checkpoint Negative Regulation Of Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To Ionizing Radiation Positive Regulation Of Telomere Maintenance Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Tubulin N-terminal-methionine Acetyltransferase Activity Regulation Of Cell Cycle Regulation Of Protein-containing Complex Assembly Regulation Of DNA Biosynthetic Process Positive Regulation Of Cellular Component Organization Protein Localization To Chromosome Regulation Of G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Regulation Of Organelle Organization Regulation Of Mitotic Cell Cycle Positive Regulation Of Macroautophagy DNA Damage Checkpoint Signaling ATR-ATRIP Complex PML Body Response To Type II Interferon GBD Domain Binding Storage Vacuole Response To Vitamin B2 C/EBP Complex Positive Regulation Of Cellular Component Biogenesis Regulation Of Mitotic Nuclear Division
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