SCAF11

Description		SR-related CTD associated factor 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Morning person ( 30696823) Multiple sclerosis ( 31604244) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278)
Novel Interacting Genes		14 novel interacting genes: ATXN1L PSEN1 RNF10 SHMT2 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 SUMO2 TUBA1C U2AF2
Interacting Genes		14 interacting genes: ATXN1L PSEN1 RNF10 SHMT2 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 SUMO2 TUBA1C U2AF2
Entrez ID		9169
HPRD ID		04720
Ensembl ID		ENSG00000139218
Uniprot IDs		F8VXG7 Q99590
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Splicing MRNA Metabolic Process Nuclear Speck MRNA Processing RNA Binding Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Nucleus MRNA Binding RNA Processing Nucleic Acid Binding Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of RNA Splicing Postsynapse To Nucleus Signaling Pathway Regulation Of Metabolic Process Nucleoplasm Cellular Response To Interleukin-17 RNA Splicing, Via Transesterification Reactions Primary MiRNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Response To Cytokine Sequence-specific MRNA Binding Response To Peptide Negative Regulation Of MRNA Metabolic Process U2-type Prespliceosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Catabolic Process Negative Regulation Of RNA Splicing Cellular Response To Cytokine Stimulus Negative Regulation Of Macromolecule Metabolic Process Spliceosomal Complex Positive Regulation Of ATP Metabolic Process Signal Transduction Involved In Regulation Of Gene Expression Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process
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