PCSK7

Description		proprotein convertase subtilisin/kexin type 7
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Endomembrane System Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Protein Processing Peptide Hormone Processing
Pathways		Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 21943158) HDL cholesterol ( 24507774 31170924) Iron status biomarkers ( 21149283) Refractive error ( 32231278) Triglyceride levels ( 26763881) Triglycerides ( 24507774)
Novel Interacting Genes		7 novel interacting genes: CSDE1 HNRNPD HSPA5 PABPC1 PMCH SYNCRIP TRIM54
Interacting Genes		7 interacting genes: CSDE1 HNRNPD HSPA5 PABPC1 PMCH SYNCRIP TRIM54
Entrez ID		9159
HPRD ID		05339
Ensembl ID		ENSG00000160613
Uniprot IDs		Q16549
PDB IDs
Enriched GO Terms of Interacting Partners?		MCRD-mediated MRNA Stability Complex CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Cytoplasmic Translation MRNA Stabilization Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability CRD-mediated MRNA Stability Complex Positive Regulation Of Protein Metabolic Process Regulation Of MRNA Metabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Catabolic Process Regulation Of Translation Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleic Acid Binding Post-transcriptional Regulation Of Gene Expression RNA Catabolic Process Regulation Of Protein Metabolic Process MRNA Binding Nucleobase-containing Compound Catabolic Process Macromolecule Catabolic Process Hepatocyte Dedifferentiation Ribonucleoprotein Complex Cellular Response To Putrescine Regulation Of Protein Folding In Endoplasmic Reticulum Type 1 Melanin-concentrating Hormone Receptor Binding Melanin-concentrating Hormone Activity Catalytic Step 2 Spliceosome Negative Regulation Of Gene Expression Cytoplasmic Stress Granule Positive Regulation Of Gene Expression Circadian Regulation Of Translation Cerebellum Structural Organization Negative Regulation Of Synaptic Transmission, Dopaminergic Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of MRNA Catabolic Process MRNA Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Negative Regulation Of RNA Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of MRNA Metabolic Process
Tagcloud ?