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USP14

Description ubiquitin specific peptidase 14
Image
GO Annotations Cellular Component
  • Proteasome Complex
  • Nucleus
  • Cytosol
  • Plasma Membrane
  • Cell Surface
  • Cytoplasmic Vesicle
  • Extracellular Exosome
Molecular Function
  • Cysteine-type Endopeptidase Activity
  • Thiol-dependent Ubiquitin-specific Protease Activity
  • Endopeptidase Inhibitor Activity
  • Protein Binding
  • Proteasome Binding
Biological Process
  • Ubiquitin-dependent Protein Catabolic Process
  • Negative Regulation Of Endopeptidase Activity
  • Protein Deubiquitination
  • Protein Phosphopantetheinylation
  • Innate Immune Response
  • Regulation Of Chemotaxis
  • Regulation Of Proteasomal Protein Catabolic Process
  • Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
Pathways
  • Ub-specific processing proteases
Drugs
  • Phenethyl Isothiocyanate
Diseases
GWAS
Interacting Genes 11 interacting genes: COPS5 CXCR4 FANCC SEM1 SPAG5-AS1 TRIM11 UBC USP15 USP21 USP28 XRCC6
Entrez ID 9097
HPRD ID 06279
Ensembl ID ENSG00000101557
Uniprot IDs P54578
PDB IDs 2AYN 2AYO 5GJQ 6IIK 6IIL 6IIM 6IIN 6LVS
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025