NAT8

Description		N-acetyltransferase 8 (putative)
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups L-cysteine-S-conjugate N-acetyltransferase Activity Protein-lysine-acetyltransferase Activity
	Biological Process	Glutathione Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Amyloid Fibril Formation
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Macrovascular complications in type 2 diabetes ( 33430853) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 33838163 29545352) Serum metabolite levels ( 33031748 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)
Novel Interacting Genes		38 novel interacting genes: AQP6 ARL13B ATP6V0E1 BIK CD3E CD59 CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MTIF3 NAT8B REEP2 SAR1A SLC10A6 SLC40A1 SLC71A2 SMAD4 SMYD5 SSB ST6GAL1 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TRIM21 TSPAN31 YIPF4
Interacting Genes		38 interacting genes: AQP6 ARL13B ATP6V0E1 BIK CD3E CD59 CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MTIF3 NAT8B REEP2 SAR1A SLC10A6 SLC40A1 SLC71A2 SMAD4 SMYD5 SSB ST6GAL1 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TRIM21 TSPAN31 YIPF4
Entrez ID		9027
HPRD ID		08413
Ensembl ID		ENSG00000144035
Uniprot IDs		Q9UHE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum
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