RPS6KA4

Description		ribosomal protein S6 kinase A4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Synapse
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Histone H3S10 Kinase Activity Histone H3S28 Kinase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Negative Regulation Of Cytokine Production Chromatin Remodeling Regulation Of DNA-templated Transcription Protein Phosphorylation Inflammatory Response Positive Regulation Of CREB Transcription Factor Activity Intracellular Signal Transduction TORC1 Signaling Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Interleukin-1-mediated Signaling Pathway
Pathways		Recycling pathway of L1
Drugs		Flavin mononucleotide
Diseases
GWAS		Cervical high-risk human papilloma virus infection ( 33225922) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233) Leprosy ( 22019778) Offspring birth weight ( 31043758) Primary biliary cholangitis ( 21399635) Primary biliary cirrhosis ( 22961000) Psoriasis ( 23143594) Serum uric acid levels ( 32514006)
Novel Interacting Genes		10 novel interacting genes: ATF1 CREB1 FOS HMGN1 MAP2K1 MAPK1 MAPK14 MAPK3 NEDD4 PDE2A
Interacting Genes		10 interacting genes: ATF1 CREB1 FOS HMGN1 MAP2K1 MAPK1 MAPK14 MAPK3 NEDD4 PDE2A
Entrez ID		8986
HPRD ID		04677
Ensembl ID		ENSG00000162302
Uniprot IDs		A0PJF8 B4DPV1 E9PJN1 O75676
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Golgi Inheritance Intracellular Signaling Cassette Regulation Of Transcription By RNA Polymerase II Trachea Formation Response To Growth Factor Intracellular Signal Transduction ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Cytokine Stimulus Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process MAP Kinase Activity Regulation Of Golgi Organization Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Regulation Of Nucleobase-containing Compound Metabolic Process Response To Peptide Response To Cytokine Regulation Of Intracellular Transport Cellular Response To Tumor Necrosis Factor Face Development Animal Organ Formation Stress-activated MAPK Cascade ERBB2 Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Lung Morphogenesis Positive Regulation Of Biosynthetic Process Response To Tumor Necrosis Factor Response To Light Stimulus Enzyme-linked Receptor Protein Signaling Pathway Thyroid Gland Development Astrocyte Differentiation Insulin-like Growth Factor Receptor Signaling Pathway Interleukin-34-mediated Signaling Pathway Response To Purine-containing Compound Regulation Of Stress-activated MAPK Cascade Myeloid Leukocyte Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Lipopolysaccharide-mediated Signaling Pathway Regulation Of Stress-activated Protein Kinase Signaling Cascade Response To Lipid ATF4-CREB1 Transcription Factor Complex DNA-templated Transcription Regulation Of Gene Expression Osteoclast Differentiation Response To Radiation
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