UNC5C

Description		unc-5 netrin receptor C
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Lamellipodium Filopodium Axon Dendrite Growth Cone Cell Projection Neuron Projection Neuronal Cell Body Synapse
	Molecular Function	Netrin Receptor Activity Netrin Receptor Activity Involved In Chemorepulsion Protein Binding Tubulin Binding Protein Kinase Binding
	Biological Process	Apoptotic Process Signal Transduction Axon Guidance Brain Development Regulation Of Cell Migration Anterior/posterior Axon Guidance Ectopic Germ Cell Programmed Cell Death Netrin-activated Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Developmental Process Chemorepulsion Of Axon Dorsal Root Ganglion Development Positive Regulation Of Reproductive Process Regulation Of Neuron Migration
Pathways		Netrin mediated repulsion signals Netrin mediated repulsion signals
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol dependence symptom count ( 29460428) Blood protein levels ( 30072576) Cerebrospinal P-tau181p levels ( 20932310) Coronary artery disease ( 29212778) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Major depressive disorder ( 29317602) Maximum stenosis ( 32469969) Myocardial infarction ( 33532862) Obesity-related traits ( 23251661) Obsessive-compulsive symptoms ( 26859814) Optic nerve measurement (cup-to-disc ratio) ( 20395239) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Residual cognition ( 28441426) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Type 2 diabetes ( 31049640)
Novel Interacting Genes		2 novel interacting genes: DAPK1 NTN1
Interacting Genes		2 interacting genes: DAPK1 NTN1
Entrez ID		8633
HPRD ID		04678
Ensembl ID		ENSG00000182168
Uniprot IDs		A8K385 O95185
PDB IDs
Enriched GO Terms of Interacting Partners?		DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Regulation Of NMDA Receptor Activity Actin Cytoskeleton Cdc42 Protein Signal Transduction Cellular Response To Hydroperoxide Defense Response To Tumor Cell Glutamatergic Synapse Chemorepulsion Of Axon Substrate-dependent Cell Migration, Cell Extension Anterior/posterior Axon Guidance Mammary Gland Duct Morphogenesis Motor Neuron Migration Apoptotic Process Calcium/calmodulin-dependent Protein Kinase Activity Response To Hydroperoxide Regulation Of Neurotransmitter Receptor Activity Syntaxin-1 Binding Positive Regulation Of Glial Cell Proliferation Regulation Of Glial Cell Migration Cell Death Programmed Cell Death Regulation Of Response To Tumor Cell Nucleus Localization Glial Cell Proliferation Negative Regulation Of Axon Extension Nuclear Migration Regulation Of Signaling Receptor Activity Organelle Mammary Gland Development Positive Regulation Of Axon Extension Regulation Of Glial Cell Proliferation Negative Chemotaxis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Axonogenesis Inner Ear Morphogenesis Positive Regulation Of Gliogenesis Rho Protein Signal Transduction
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