GPT2

Description		glutamic--pyruvic transaminase 2
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	L-alanine:2-oxoglutarate Aminotransferase Activity Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding
	Biological Process	2-oxoglutarate Metabolic Process L-alanine Metabolic Process L-alanine Catabolic Process
Pathways
Drugs		Pyridoxal phosphate Glutamic acid Alanine Phenelzine
Diseases
GWAS
Novel Interacting Genes		4 novel interacting genes: AKT1 APP HEATR3 OGT
Interacting Genes		4 interacting genes: AKT1 APP HEATR3 OGT
Entrez ID		84706
HPRD ID		06307
Ensembl ID		ENSG00000166123
Uniprot IDs		Q8TD30
PDB IDs		3IHJ
Enriched GO Terms of Interacting Partners?		Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Proteolysis Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Synapse Organization Response To Nerve Growth Factor Negative Regulation Of Translational Initiation Phosphatidylinositol-3,4,5-trisphosphate Binding Regulation Of Proteolysis Regulation Of Small Molecule Metabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Translational Initiation Positive Regulation Of Nitric Oxide Metabolic Process Cellular Response To Nerve Growth Factor Stimulus Regulation Of Translation Regulation Of Glycolytic Process Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of TORC1 Signaling Regulation Of Nitric Oxide Metabolic Process TORC1 Signaling Regulation Of Carbohydrate Catabolic Process Regulation Of Lymphocyte Migration Negative Regulation Of Protein Ubiquitination Regulation Of ATP Metabolic Process Protein Localization To Organelle Regulation Of Phosphorus Metabolic Process TOR Signaling Regulation Of TORC1 Signaling Regulation Of Glucose Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation Negative Regulation Of Post-translational Protein Modification Positive Regulation Of TOR Signaling Positive Regulation Of Lipid Biosynthetic Process Regulation Of TRNA Methylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Import Into Nucleus Cytoplasmic Translation Import Into Nucleus Positive Regulation Of Mitotic Cell Cycle Protein-containing Complex Positive Regulation Of Protein Localization To Endoplasmic Reticulum
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