TEX101

Description		testis expressed 101
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GO Annotations	Cellular Component	Acrosomal Vesicle Acrosomal Membrane Extracellular Region Plasma Membrane Membrane Cytoplasmic Vesicle Plasma Membrane Raft Membrane Raft Side Of Membrane
	Molecular Function	Protein Binding
	Biological Process	Binding Of Sperm To Zona Pellucida Fertilization Flagellated Sperm Motility Regulation Of Flagellated Sperm Motility
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Cotinine glucuronidation ( 25293881)
Novel Interacting Genes		3 novel interacting genes: BRCA1 KLHL8 PICK1
Interacting Genes		3 interacting genes: BRCA1 KLHL8 PICK1
Entrez ID		83639
HPRD ID		15490
Ensembl ID		ENSG00000131126
Uniprot IDs		Q9BY14
PDB IDs		7BPR
Enriched GO Terms of Interacting Partners?		Protein Modification Process Negative Regulation Of Centriole Replication BRCA1-A Complex BRCA1-B Complex Histone H2AK127 Ubiquitin Ligase Activity Negative Regulation Of Cytoskeleton Organization Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol BRCA1-C Complex Ubiquitin-modified Histone Reader Activity Histone H2AK129 Ubiquitin Ligase Activity Response To Indole-3-methanol BRCA1-BARD1 Complex Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Negative Regulation Of Centrosome Duplication Lateral Element Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Gamma-tubulin Ring Complex DNA Strand Resection Involved In Replication Fork Processing DNA Repair Complex Random Inactivation Of X Chromosome Neuronal Ion Channel Clustering Arp2/3 Complex Binding Dendritic Spine Maintenance XY Body Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Regulation Of Cytoskeleton Organization Long-term Synaptic Depression RNA Polymerase Binding Negative Regulation Of Fatty Acid Biosynthetic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Protein Ubiquitination Regulation Of DNA Damage Checkpoint Negative Regulation Of Cellular Component Organization Protein K6-linked Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Centriole Replication Protein Metabolic Process Positive Regulation Of Receptor Internalization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Positive Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Condensed Chromosome Mitotic G2 DNA Damage Checkpoint Signaling Postreplication Repair Dendritic Spine Organization
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