SLC7A5

Description		solute carrier family 7 member 5
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Cytosol Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Microvillus Membrane Extracellular Exosome External Side Of Apical Plasma Membrane Amino Acid Transport Complex
	Molecular Function	Protein Binding Amino Acid Transmembrane Transporter Activity Aromatic Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity L-tryptophan Transmembrane Transporter Activity Antiporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Positive Regulation Of Cytokine Production Involved In Immune Response Amino Acid Transmembrane Transport Amino Acid Transport Negative Regulation Of Autophagy Negative Regulation Of Gene Expression Response To Muscle Activity Neutral Amino Acid Transport L-amino Acid Transport Isoleucine Transport L-leucine Transport Methionine Transport Phenylalanine Transport Proline Transport Tryptophan Transport Tyrosine Transport Valine Transport Alanine Transport Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-17 Production Positive Regulation Of Interleukin-4 Production Cellular Response To Glucose Starvation Xenobiotic Transport Transmembrane Transport Response To Hyperoxia Positive Regulation Of Glial Cell Proliferation Thyroid Hormone Transport Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Amino Acid Import Across Plasma Membrane Liver Regeneration Transport Across Blood-brain Barrier L-histidine Transport L-alpha-amino Acid Transmembrane Transport Cellular Response To L-arginine L-leucine Import Across Plasma Membrane L-tryptophan Transmembrane Transport Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of L-leucine Import Across Plasma Membrane
Pathways		Basigin interactions Amino acid transport across the plasma membrane Tryptophan catabolism
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum metabolite levels ( 33031748)
Novel Interacting Genes		2 novel interacting genes: SLC3A2 TUBB3
Interacting Genes		2 interacting genes: SLC3A2 TUBB3
Entrez ID		8140
HPRD ID		02552
Ensembl ID		ENSG00000103257
Uniprot IDs		Q01650
PDB IDs		6IRS 6IRT 6JMQ 7DSK 7DSL 7DSN 7DSQ 8IDA 8J8L 8J8M 8KDD 8KDF 8KDG 8KDH 8KDI 8KDJ 8KDN 8KDO 8KDP 8X0W 8XPU
Enriched GO Terms of Interacting Partners?		Apical Pole Of Neuron Isoleucine Transport L-histidine Transport Exogenous Protein Binding Methionine Transport L-leucine Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Phenylalanine Transport Amino Acid Transport Complex L-alanine Transmembrane Transport Neuronal Cell Body Aromatic Amino Acid Transmembrane Transporter Activity Valine Transport Tryptophan Transport L-alanine Import Across Plasma Membrane Tyrosine Transport Netrin Receptor Binding Dorsal Root Ganglion Development L-alanine Transmembrane Transporter Activity L-alanine Transport L-leucine Transport Proline Transport Netrin-activated Signaling Pathway Aromatic Amino Acid Transport Branched-chain Amino Acid Transport Thyroid Hormone Transport Alanine Transport Sulfur Amino Acid Transport Ganglion Development Neutral L-amino Acid Transmembrane Transporter Activity Basic Amino Acid Transport Peptide Binding Amino Acid Import Across Plasma Membrane Response To Exogenous DsRNA Neutral Amino Acid Transport Response To DsRNA L-alpha-amino Acid Transmembrane Transport Basal Plasma Membrane L-amino Acid Transport Double-stranded RNA Binding Organic Cation Transport Amino Acid Transmembrane Transport Virus Receptor Activity Filopodium Intercellular Bridge Cell Periphery Hormone Transport Melanosome Structural Constituent Of Cytoskeleton Amino Acid Transport
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