BTG2

Description		BTG anti-proliferation factor 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Damage Response Neuroblast Proliferation Negative Regulation Of Neuroblast Proliferation Negative Regulation Of Cell Population Proliferation Associative Learning Response To Mechanical Stimulus Anterior/posterior Pattern Specification Negative Regulation Of Translation Dentate Gyrus Development Central Nervous System Neuron Development Neuron Differentiation Neuron Projection Development Skeletal Muscle Cell Differentiation Negative Regulation Of Apoptotic Process Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Response To Electrical Stimulus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Neural Precursor Cell Proliferation Cellular Response To Phorbol 13-acetate 12-myristate
Pathways		TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252 32888494) Red cell distribution width ( 27863252 28957414 32888494)
Novel Interacting Genes		17 novel interacting genes: CCNB1 CDK1 CNOT7 CNOT8 HOXB9 HOXC8 MAPK14 MAPK3 PICK1 PIN1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1 TNFRSF4
Interacting Genes		17 interacting genes: CCNB1 CDK1 CNOT7 CNOT8 HOXB9 HOXC8 MAPK14 MAPK3 PICK1 PIN1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1 TNFRSF4
Entrez ID		7832
HPRD ID		03357
Ensembl ID		ENSG00000159388
Uniprot IDs		P78543
PDB IDs		3DJU 3E9V
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cell Population Proliferation Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Cell Population Proliferation Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Cyclin B1-CDK1 Complex Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway BMP Signaling Pathway Positive Regulation Of RNA Metabolic Process Positive Regulation Of Cardiac Muscle Cell Proliferation Regulation Of Transcription By RNA Polymerase II Response To Stress Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of Heart Growth Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Metabolic Process Intracellular Signaling Cassette Positive Regulation Of Organ Growth Regulation Of MRNA Metabolic Process CCR4-NOT Core Complex G2/M Transition Of Mitotic Cell Cycle Mitogen-activated Protein Kinase P38 Binding SMAD Protein Complex Nucleus Cytosol Cell Cycle G2/M Phase Transition Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Heteromeric SMAD Protein Complex Regulation Of MRNA Stability Response To Mechanical Stimulus Regulation Of Heart Growth Ventricular Cardiac Muscle Cell Development Nucleic Acid Metabolic Process Regulation Of RNA Stability Mitotic Nuclear Membrane Disassembly Poly(A)-specific Ribonuclease Activity G1/S Transition Of Mitotic Cell Cycle
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