COL14A1

Description		collagen type XIV alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type XIV Trimer Interstitial Matrix Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	RNA Binding Extracellular Matrix Structural Constituent Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Protein-macromolecule Adaptor Activity
	Biological Process	Ventricular Cardiac Muscle Tissue Development Cell Adhesion Extracellular Matrix Organization Collagen Fibril Organization Homeostasis Of Number Of Cells Within A Tissue Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cell-cell Adhesion
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Collagen chain trimerization
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Appendicular lean mass ( 33097823) Cerebrospinal T-tau levels ( 28247064) Gastritis ( 25317112) Parasitemia in Tripanosoma cruzi seropositivity ( 24324551) Visceral fat ( 30942860)
Novel Interacting Genes		5 novel interacting genes: APP CD44 DCN ENO1 RNF10
Interacting Genes		5 interacting genes: APP CD44 DCN ENO1 RNF10
Entrez ID		7373
HPRD ID		00379
Ensembl ID		ENSG00000187955
Uniprot IDs		Q05707
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Metabolic Process Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Stress Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Cell Communication Regulation Of System Process Golgi Lumen Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cell Surface Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Nervous System Process Microglia Development Regulation Of Intracellular Signal Transduction Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Monocyte Aggregation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Macrophage Migration Inhibitory Factor Receptor Complex Monocyte Aggregation Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Low-density Lipoprotein Particle Mediated Signaling Carbohydrate Derivative Catabolic Process Positive Regulation Of Proteolysis Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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