UGT2B7

Description		UDP glucuronosyltransferase family 2 member B7
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Retinoic Acid Binding UDP-glycosyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	Lipid Metabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Androgen Metabolic Process Estrogen Metabolic Process
Pathways		Glucuronidation Aspirin ADME Prednisone ADME
Drugs
Diseases
GWAS		AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Estradiol levels ( 34255042) Gamma glutamyl transferase levels ( 33339817) Liver enzyme levels (alkaline phosphatase) ( 33972514) Obesity-related traits ( 23251661) Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Urinary metabolite levels in chronic kidney disease ( 31959995)
Novel Interacting Genes		2 novel interacting genes: CYP3A4 GABRA3
Interacting Genes		2 interacting genes: CYP3A4 GABRA3
Entrez ID		7364
HPRD ID		02508
Ensembl ID		ENSG00000171234
Uniprot IDs		E9PBP8 P16662
PDB IDs		2O6L
Enriched GO Terms of Interacting Partners?		Vitamin D Biosynthetic Process Quinine 3-monooxygenase Activity Anandamide 8,9 Epoxidase Activity Calcitriol Biosynthetic Process From Calciol Vitamin D 24-hydroxylase Activity Anandamide 11,12 Epoxidase Activity Vitamin D Catabolic Process 1,8-cineole 2-exo-monooxygenase Activity Anandamide 14,15 Epoxidase Activity Alkaloid Catabolic Process Vitamin D3 25-hydroxylase Activity 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase Activity Caffeine Oxidase Activity Testosterone 6-beta-hydroxylase Activity Oxidative Demethylation Vitamin D3 Metabolic Process Retinoic Acid 4-hydroxylase Activity Monoterpenoid Metabolic Process Aflatoxin Metabolic Process Lipid Hydroxylation Estrogen 16-alpha-hydroxylase Activity Estrogen 2-hydroxylase Activity Alkaloid Metabolic Process Demethylation Benzodiazepine Receptor Activity Vitamin D Metabolic Process Steroid Hydroxylase Activity Toxin Metabolic Process GABA-gated Chloride Ion Channel Activity GABA-A Receptor Activity GABA-A Receptor Complex Retinoic Acid Metabolic Process Xenobiotic Catabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Vitamin Metabolic Process Oxygen Binding Androgen Metabolic Process Steroid Catabolic Process Gamma-aminobutyric Acid Signaling Pathway Inhibitory Synapse Assembly Steroid Binding Postsynaptic Specialization Membrane Dendrite Membrane Synaptic Transmission, GABAergic Estrogen Metabolic Process Extracellular Ligand-gated Monoatomic Ion Channel Activity Long-chain Fatty Acid Biosynthetic Process Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Secondary Metabolic Process Retinol Metabolic Process
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