CCL15

Description		C-C motif chemokine ligand 15
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Cytokine Activity Chemokine Activity Heparin Binding Chemoattractant Activity CCR Chemokine Receptor Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Migration Positive Regulation Of Inflammatory Response Positive Chemotaxis Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Upper eyelid sagging severity ( 24869959)
Novel Interacting Genes		4 novel interacting genes: CCL2 CCR1 CCR3 SDF2
Interacting Genes		4 interacting genes: CCL2 CCR1 CCR3 SDF2
Entrez ID		6359
HPRD ID		03232
Ensembl ID		ENSG00000275718
Uniprot IDs		Q16663
PDB IDs		2HCC 7VL9 7VLA
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Chemokine Receptor Activity Cell Chemotaxis Monocyte Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Chemotaxis Locomotion Cytokine-mediated Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Cytokine Stimulus Inflammatory Response Response To Cytokine Response To Peptide Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Calcium Ion Transport Mononuclear Cell Migration Helper T Cell Extravasation Chemokine (C-C Motif) Ligand 2 Signaling Pathway Leukocyte Chemotaxis Regulation Of Mononuclear Cell Migration Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Myeloid Leukocyte Migration Chemokine (C-C Motif) Ligand 5 Binding Positive Regulation Of Chemotaxis Chemokine (C-C Motif) Ligand 7 Binding Regulation Of Endothelial Cell Proliferation Negative Regulation Of Natural Killer Cell Chemotaxis Cell Adhesion Cell Migration Calcium-mediated Signaling Positive Regulation Of Monoatomic Ion Transport Negative Regulation Of Lymphocyte Chemotaxis Regulation Of Chemotaxis Cell Motility CCR2 Chemokine Receptor Binding Regulation Of Leukocyte Migration Regulation Of Calcium Ion Transport Leukocyte Migration T Cell Extravasation Immune Response Astrocyte Cell Migration Defense Response Positive Regulation Of Apoptotic Cell Clearance Regulation Of Metal Ion Transport External Side Of Plasma Membrane Positive Regulation Of Glutamate Receptor Signaling Pathway
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