SERPINB3

Description		serpin family B member 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cytoplasmic Vesicle Vesicle Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protease Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Negative Regulation Of Peptidase Activity Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Endopeptidase Activity Negative Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Autocrine Signaling Paracrine Signaling Negative Regulation Of Catalytic Activity Negative Regulation Of JUN Kinase Activity Negative Regulation Of Proteolysis Symbiont Entry Into Host Cell
Pathways		Neutrophil degranulation
Drugs		D-Serine Dexfosfoserine
Diseases
GWAS
Novel Interacting Genes		7 novel interacting genes: CDC42 CTSK CTSL CTSS MAPK8 SLC26A4-AS1 UCHL5
Interacting Genes		7 interacting genes: CDC42 CTSK CTSL CTSS MAPK8 SLC26A4-AS1 UCHL5
Entrez ID		6317
HPRD ID		02745
Ensembl ID		ENSG00000057149
Uniprot IDs		P29508
PDB IDs		2ZV6 4ZK0 4ZK3
Enriched GO Terms of Interacting Partners?		Endolysosome Lumen Proteoglycan Binding Cysteine-type Peptidase Activity Fibronectin Binding Collagen Catabolic Process Collagen Metabolic Process Cysteine-type Endopeptidase Activity Collagen Binding Lysosomal Lumen Cellular Response To Thyroid Hormone Stimulus Peptidase Activity Response To Thyroid Hormone Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Proteolysis Involved In Protein Catabolic Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Hydrolase Activity Extracellular Matrix Disassembly Antigen Processing And Presentation Of Exogenous Antigen Antigen Processing And Presentation Of Peptide Antigen Serpin Family Protein Binding Fusion Of Virus Membrane With Host Endosome Membrane JUN Phosphorylation Phagocytic Vesicle Proteolysis Lysosome Antigen Processing And Presentation GBD Domain Binding Storage Vacuole Enkephalin Processing Endothelin Receptor Signaling Pathway Involved In Heart Process Macrophage Apoptotic Process Elastin Catabolic Process Fusion Of Virus Membrane With Host Plasma Membrane Basement Membrane Disassembly JUN Kinase Activity Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Serine-type Endopeptidase Activity Chromaffin Granule Elastin Metabolic Process Histone Deacetylase Regulator Activity Basal Dendrite Protein Metabolic Process Protein Processing Hormone Metabolic Process Inflammatory Cell Apoptotic Process Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process
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