EP400

Description		E1A binding protein p400
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GO Annotations	Cellular Component	Nucleosome Swr1 Complex Nucleus Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	Nucleotide Binding DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity Protein Antigen Binding
	Biological Process	DNA Repair Chromatin Organization Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 27863252 28957414 32888494)
Novel Interacting Genes		15 novel interacting genes: ALAS1 ATM BRD8 CEBPA KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT
Interacting Genes		15 interacting genes: ALAS1 ATM BRD8 CEBPA KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT
Entrez ID		57634
HPRD ID		09378
Ensembl ID		ENSG00000183495
Uniprot IDs		Q96L91
PDB IDs		8QR1 8QRI 8XVG 8XVT 8XVV 9C47 9C57 9C62 9C6N
Enriched GO Terms of Interacting Partners?		Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of DNA Recombination Swr1 Complex Nucleoplasm Positive Regulation Of DNA Recombination Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair NuA4 Histone Acetyltransferase Complex Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of DNA Repair Regulation Of Cell Cycle Cellular Response To Oxygen-containing Compound Response To Xenobiotic Stimulus Site Of Double-strand Break Nucleolus Positive Regulation Of Chromosome Organization Transcription By RNA Polymerase I Nucleosome Protein-containing Complex Binding Positive Regulation Of RNA Biosynthetic Process DNA Double-strand Break Processing Response To X-ray Cellular Response To Gamma Radiation Regulation Of Nucleobase-containing Compound Metabolic Process Recombinational Repair Reciprocal Meiotic Recombination Response To Ionizing Radiation Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA-templated Transcription Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Localization To Site Of Double-strand Break DNA Repair-dependent Chromatin Remodeling Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Radiation Intrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Response To Radiation DNA-binding Transcription Factor Binding Homologous Recombination Chromatin Organization Meiosis I
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