AKIP1

Description		A-kinase interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Protein Binding
	Biological Process	Substrate Adhesion-dependent Cell Spreading Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Brain morphology (MOSTest) ( 32665545) Hemoglobin levels ( 32327693)
Novel Interacting Genes		8 novel interacting genes: BARD1 FHL2 HMGB1 MAPK13 MCPH1 PRKACA QSOX1 SPTAN1
Interacting Genes		8 interacting genes: BARD1 FHL2 HMGB1 MAPK13 MCPH1 PRKACA QSOX1 SPTAN1
Entrez ID		56672
HPRD ID		12380
Ensembl ID		ENSG00000166452
Uniprot IDs		Q9NQ31
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Histone H2AK127 Ubiquitin Ligase Activity Regulation Of Protein Export From Nucleus Negative Regulation Of Metabolic Process Histone H2AK129 Ubiquitin Ligase Activity Negative Regulation Of MRNA 3'-end Processing BRCA1-BARD1 Complex Atrial Cardiac Muscle Cell Development Regulation Of Calcium-mediated Signaling Positive Regulation Of Glucose Metabolic Process Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Interleukin-6 Production Regulation Of Glucose Metabolic Process Regulation Of Autophagy Positive Regulation Of Myeloid Progenitor Cell Differentiation Negative Regulation Of Apoptotic Cell Clearance Cellular Response To Carbohydrate Stimulus Cellular Response To Sorbitol Specific Granule Lumen Tertiary Granule Lumen Regulation Of Phagocytosis BRCA1-B Complex Regulation Of Nucleocytoplasmic Transport Regulation Of Mismatch Repair C-X-C Chemokine Binding Negative Regulation Of Protein-containing Complex Assembly Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Response To Anisomycin Cellular Response To Anisomycin Response To Sorbitol Flavin-dependent Sulfhydryl Oxidase Activity Regulation Of Intracellular Protein Transport Negative Regulation Of RNA Metabolic Process Nuclear Ubiquitin Ligase Complex BRCA1-C Complex Cellular Response To Radiation Negative Regulation Of Macromolecule Metabolic Process Response To Hormone Negative Regulation Of DNA-templated Transcription Initiation
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