KDM3A

Description		lysine demethylase 3A
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Chromatin Binding Transcription Coregulator Activity Iron Ion Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity Chromatin DNA Binding Histone H3K9 Demethylase Activity Metal Ion Binding Nuclear Androgen Receptor Binding Dioxygenase Activity Histone H3K9me/H3K9me2 Demethylase Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Spermatogenesis Spermatid Nucleus Elongation Hormone-mediated Signaling Pathway Regulation Of Gene Expression Cell Differentiation Androgen Receptor Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Formaldehyde Biosynthetic Process Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Leukemia Inhibitory Factor Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation
Pathways		HDMs demethylate histones NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Glomerular filtration rate in chronic kidney disease ( 26420894) Ovarian cancer ( 30557369)
Novel Interacting Genes		7 novel interacting genes: BTG3 ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Interacting Genes		7 interacting genes: BTG3 ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Entrez ID		55818
HPRD ID		11054
Ensembl ID		ENSG00000115548
Uniprot IDs		Q9Y4C1
PDB IDs
Enriched GO Terms of Interacting Partners?		Smooth Muscle Cell Differentiation Positive Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Coactivator Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Blood Vessel Morphogenesis Positive Regulation Of Developmental Process Positive Regulation Of Mesoderm Development Positive Regulation Of Macromolecule Biosynthetic Process Response To Interleukin-18 Regulation Of Cell Growth By Extracellular Stimulus Positive Regulation Of Biosynthetic Process Response To Interleukin-12 Cardiac Vascular Smooth Muscle Cell Differentiation Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Urinary Bladder Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Mesoderm Development Positive Regulation Of T-helper 1 Cell Differentiation Toll-like Receptor 2 Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway LIM Domain Binding Cellular Response To Peptidoglycan Immature T Cell Proliferation In Thymus Xenophagy Positive Regulation Of Immature T Cell Proliferation In Thymus Protein Linear Polyubiquitination Ventricular Cardiac Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Cell Differentiation Cardiac Ventricle Development Ductus Arteriosus Closure Regulation Of Phenotypic Switching Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Xenophagy Positive Regulation Of Protein K63-linked Ubiquitination Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Tagcloud ?