USP47

Description		ubiquitin specific peptidase 47
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity WD40-repeat Domain Binding Deubiquitinase Activity
	Biological Process	DNA Repair Base-excision Repair Proteolysis DNA Damage Response Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Deubiquitination Regulation Of Protein Stability Monoubiquitinated Protein Deubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)
Novel Interacting Genes		9 novel interacting genes: AP4M1 DSCR9 MED29 MED9 PLA2G2A RPS2 SNCA TLE3 UBC
Interacting Genes		9 interacting genes: AP4M1 DSCR9 MED29 MED9 PLA2G2A RPS2 SNCA TLE3 UBC
Entrez ID		55031
HPRD ID		11668
Ensembl ID		ENSG00000170242
Uniprot IDs		Q96K76
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Outer Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Mediator Complex Core Mediator Complex Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Protein Localization To Basolateral Plasma Membrane Regulation Of DNA-templated Transcription Elongation Phospholipid Binding Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake AP-4 Adaptor Complex Transcription Coregulator Activity Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process
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