DPP8

Description		dipeptidyl peptidase 8
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Aminopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Apoptotic Process Immune Response Negative Regulation Of Programmed Cell Death Protein Maturation CARD8 Inflammasome Complex Assembly Pyroptotic Cell Death NLRP1 Inflammasome Complex Assembly
Pathways
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 20139978 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Red blood cell count ( 29403010 32888494)
Novel Interacting Genes		1 novel interacting genes: AFF3
Interacting Genes
Entrez ID		54878
HPRD ID		07076
Ensembl ID		ENSG00000074603
Uniprot IDs		A8K4U2 B4DLA8 Q6V1X1
PDB IDs		6EOO 6EOP 6EOS 6EOT 6HP8 6QZW 6TRW 6TRX 7A3G 7A3I 7A3J 7A3K 7A3L 7AYQ 7AYR 7OR4 7OZ7 7SVM 7SVO
Enriched GO Terms of Interacting Partners?		Super Elongation Complex Hindlimb Morphogenesis Embryonic Hindlimb Morphogenesis Limb Morphogenesis Embryonic Limb Morphogenesis Response To Tumor Necrosis Factor Double-stranded DNA Binding
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