PNLIP

Description		pancreatic lipase
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Lipoprotein Lipase Activity Triacylglycerol Lipase Activity Phospholipase A1 Activity Lipase Activity Hydrolase Activity Metal Ion Binding All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Retinyl-palmitate Esterase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Retinoid Metabolic Process Lipid Metabolic Process Fatty Acid Biosynthetic Process Lipid Catabolic Process Triglyceride Catabolic Process Intestinal Cholesterol Absorption High-density Lipoprotein Particle Remodeling Retinol Metabolic Process Cholesterol Homeostasis Positive Regulation Of Triglyceride Lipase Activity
Pathways		Digestion of dietary lipid Retinoid metabolism and transport Developmental Lineage of Pancreatic Acinar Cells
Drugs		Orlistat B-nonylglucoside (Hydroxyethyloxy)Tri(Ethyloxy)Octane Cetilistat METHOXYUNDECYLPHOSPHINIC ACID Chlortetracycline
Diseases
GWAS		Anger ( 24489884) Body mass index ( 26426971)
Novel Interacting Genes		2 novel interacting genes: CLPS YWHAE
Interacting Genes		2 interacting genes: CLPS YWHAE
Entrez ID		5406
HPRD ID		02005
Ensembl ID		ENSG00000175535
Uniprot IDs		P16233
PDB IDs		1GPL 1LPA 1LPB 1N8S
Enriched GO Terms of Interacting Partners?		Regulation Of Heart Rate By Hormone Regulation Of Heart Rate By Chemical Signal Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Phosphoserine Residue Binding Positive Regulation Of Toll-like Receptor Signaling Pathway Digestion Response To Food Lipase Binding Regulation Of Hippo Signaling Membrane Repolarization During Action Potential Calcium Channel Regulator Activity Cell Surface Toll-like Receptor Signaling Pathway Potassium Channel Regulator Activity Protein Localization To Endoplasmic Reticulum Regulation Of Protein Export From Nucleus Hippo Signaling MHC Class II Protein Complex Binding Protein Sequestering Activity Substantia Nigra Development Regulation Of Membrane Repolarization Protein K11-linked Ubiquitination Regulation Of Heart Rate By Cardiac Conduction Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Export From Nucleus Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Hippo Signaling Phosphoprotein Binding Molecular Function Inhibitor Activity Calcium Channel Inhibitor Activity Cardiac Conduction Intracellular Potassium Ion Homeostasis Potassium Ion Homeostasis Protein Phosphatase Inhibitor Activity Negative Regulation Of Calcium Ion Transport Cellular Response To Heat Cell Surface Pattern Recognition Receptor Signaling Pathway Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Neural Nucleus Development Positive Regulation Of Nucleocytoplasmic Transport Golgi To Plasma Membrane Transport Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Hippocampus Development Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
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