MT-ND5

Description		NADH dehydrogenase subunit 5
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Response To Hypoxia Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly Response To Hydrogen Peroxide ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis
Pathways		Mitochondrial translation termination Respiratory electron transport Complex I biogenesis Mitochondrial protein degradation
Drugs		NADH
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Novel Interacting Genes		2 novel interacting genes: GLUL LIG4
Interacting Genes		2 interacting genes: GLUL LIG4
Entrez ID		4540
HPRD ID		02467
Ensembl ID		ENSG00000198786
Uniprot IDs		P03915 U5ZC31
PDB IDs		5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Glutamine Synthetase Activity Intracellular Ammonium Homeostasis Ligase Activity Glutamine Biosynthetic Process Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Ammonium Homeostasis Nucleotide-excision Repair, DNA Gap Filling L-glutamate Catabolic Process DNA-dependent Protein Kinase-DNA Ligase 4 Complex Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Regulation Of Protein Localization To Nucleolus Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Lymphoid Progenitor Cell Differentiation AMP Binding Cell Population Proliferation Cellular Response To Lithium Ion Dicarboxylic Acid Catabolic Process Protein Palmitoylation Glutamine Metabolic Process Response To Lithium Ion Regulation Of Cell Development Protein-cysteine S-palmitoyltransferase Activity V(D)J Recombination Positive Regulation Of Cell Differentiation Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Glial Cell Projection Protein Lipidation Somatic Diversification Of Immunoglobulins Involved In Immune Response Response To X-ray Glutamate Metabolic Process Positive Regulation Of Erythrocyte Differentiation Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Somatic Cell DNA Recombination T Cell Differentiation In Thymus Somatic Diversification Of Immunoglobulins Fibroblast Proliferation ATP Binding Regulation Of Sprouting Angiogenesis
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