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LAIR1
Description
leukocyte associated immunoglobulin like receptor 1
Image
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Specific Granule Membrane
Tertiary Granule Membrane
Molecular Function
Protein Binding
Biological Process
Adaptive Immune Response
Immune System Process
Immune Response-regulating Signaling Pathway
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Neutrophil degranulation
Drugs
Diseases
GWAS
Novel Interacting Genes
13 novel interacting genes:
APP
CENPB
CFL2
CNOT3
COL1A1
CSK
KIR3DS1
LAIR2
MYH3
PRKCG
PTPN11
PTPN6
PTPRH
Interacting Genes
13 interacting genes:
APP
CENPB
CFL2
CNOT3
COL1A1
CSK
KIR3DS1
LAIR2
MYH3
PRKCG
PTPN11
PTPN6
PTPRH
Entrez ID
3903
HPRD ID
04292
Ensembl ID
ENSG00000167613
Uniprot IDs
A0A0G2JMI0
A0A0G2JNK8
A0A140T8W3
A8MZ84
D3YTC8
Q6GTX8
PDB IDs
3KGR
3RP1
7F9L
7F9M
7F9N
Enriched GO Terms of Interacting Partners
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Face Morphogenesis
T Cell Costimulation
Negative Regulation Of Neutrophil Activation
Myeloid Cell Development
Regulation Of Immune Response
Non-membrane Spanning Protein Tyrosine Phosphatase Activity
Protein Dephosphorylation
Regulation Of Neutrophil Activation
Neutrophil Activation Involved In Immune Response
Regulation Of ERK1 And ERK2 Cascade
Protein Tyrosine Phosphatase Activity
Negative Regulation Of Cell Adhesion
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Insulin Receptor Binding
Myeloid Leukocyte Activation
Negative Regulation Of T Cell Activation
Peptidyl-tyrosine Dephosphorylation
Phosphoprotein Phosphatase Activity
Platelet Formation
Dephosphorylation
Megakaryocyte Development
Positive Regulation Of Cell Activation
Regulation Of Interleukin-6 Production
Immune Response-regulating Signaling Pathway
Negative Regulation Of Leukocyte Cell-cell Adhesion
Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Neutrophil Activation
Cell Activation Involved In Immune Response
Negative Regulation Of T Cell Receptor Signaling Pathway
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Lymphocyte Activation
Hemopoiesis
Response To Mechanical Stimulus
Sarcomere Organization
Cell-cell Junction
Protein Tyrosine Kinase Binding
Negative Regulation Of Leukocyte Activation
Negative Regulation Of Cell-cell Adhesion
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Type I Interferon-mediated Signaling Pathway
Negative Regulation Of Protein Localization
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Immune System Process
Regulation Of Response To Calcium Ion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Leukocyte Activation
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Vitamin E
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