ID4

Description		inhibitor of DNA binding 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Dimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Transcription Regulator Inhibitor Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Positive Regulation Of Neuroblast Proliferation Neuroblast Proliferation Brain Development Circadian Rhythm Intracellular Protein Localization Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Hippocampus Development Cerebral Cortex Neuron Differentiation Central Nervous System Neuron Differentiation Central Nervous System Myelination Neuron Differentiation Fat Cell Differentiation Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Neuron Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Astrocyte Differentiation Oligodendrocyte Differentiation Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Prostate Gland Morphogenesis Prostate Gland Epithelium Morphogenesis Prostate Gland Stromal Morphogenesis Seminal Vesicle Morphogenesis
Pathways		NGF-stimulated transcription Formation of the nephric duct
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Age at voice drop ( 27182965) Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Appendicular lean mass ( 33097823) Automobile speeding propensity ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronic obstructive pulmonary disease ( 30804561) Chronotype ( 30696823) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Endometriosis ( 23472165 28333195 28537267) Free thyroxine concentration ( 30367059) Height ( 28552196 20881960) Hip circumference adjusted for BMI ( 34021172) Loneliness (multivariate analysis) ( 27629369) Response to statin therapy ( 20339536) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		5 novel interacting genes: GRIN2A HES1 ID3 MYOD1 TCF4
Interacting Genes		5 interacting genes: GRIN2A HES1 ID3 MYOD1 TCF4
Entrez ID		3400
HPRD ID		08995
Ensembl ID		ENSG00000172201
Uniprot IDs		P47928
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity E-box Binding Cell Differentiation Cellular Response To Oxygen-containing Compound Cell Fate Determination Cellular Response To Fatty Acid BHLH Transcription Factor Binding Cellular Developmental Process Animal Organ Development Regulation Of Cell Differentiation Muscle Cell Development Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Cellular Response To Lipid Trochlear Nerve Development Response To Fatty Acid Cellular Response To Tumor Necrosis Factor Cellular Response To Leptomycin B Regulation Of Myoblast Differentiation Leptomycin B Binding Sequence-specific Double-stranded DNA Binding Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Response To Tumor Necrosis Factor Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Muscle Organ Development Myoblast Fate Determination Directional Locomotion Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Timing Of Neuron Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Ureteric Bud Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Amacrine Cell Differentiation Embryonic Organ Development Negative Regulation Of Pro-B Cell Differentiation Cell Fate Commitment Regulation Of Mitotic Cell Cycle, Embryonic HLH Domain Binding Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Stomach Neuroendocrine Cell Differentiation Response To Aroclor 1254 Regulation Of Forebrain Neuron Differentiation
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