HOXD8

Description		homeobox D8
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Axis Specification, Embryo Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Skeletal System Morphogenesis
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 30604766 31015462 31152163) Glomerular filtration rate (creatinine) ( 28452372) Male-pattern baldness ( 28196072) Urate levels ( 31578528)
Novel Interacting Genes		9 novel interacting genes: ANXA7 BAIAP2 CDKN1A DYNC1I2 HMGB1 LDLRAP1 NCK2 PFDN1 RCC1
Interacting Genes		9 interacting genes: ANXA7 BAIAP2 CDKN1A DYNC1I2 HMGB1 LDLRAP1 NCK2 PFDN1 RCC1
Entrez ID		3234
HPRD ID		00868
Ensembl ID		ENSG00000175879
Uniprot IDs		A0A0A0MSX5 P13378
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Cytoskeletal Anchor Activity Positive Regulation Of Leukocyte Proliferation Signaling Receptor Complex Adaptor Activity Vesicle Membrane Cytoplasm Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Phosphotyrosine Residue Binding Positive Regulation Of Actin Filament Polymerization Phosphatidylserine Binding Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell Population Proliferation PCNA-p21 Complex Cell Cycle G1/S Phase Transition Negative Regulation Of Cardiac Muscle Tissue Regeneration G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Activation Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Myeloid Progenitor Cell Differentiation Negative Regulation Of Apoptotic Cell Clearance Regulation Of Supramolecular Fiber Organization Amyloid-beta Binding Positive Regulation Of Protein Polymerization Signaling Adaptor Activity Scaffold Protein Binding Dendritic Spine Cytoplasm Neuron Projection Branch Point Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Receptor-mediated Endocytosis Involved In Cholesterol Transport Regulation Of Protein-containing Complex Assembly Positive Regulation Of T Cell Proliferation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Positive Regulation Of Mismatch Repair Positive Regulation Of Intracellular Cholesterol Transport Regulation Of Lymphocyte Activation Cellular Response To Cell-matrix Adhesion Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress
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