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GUCA1A

Description guanylate cyclase activator 1A
Image No pdb structure
GO Annotations Cellular Component
  • Photoreceptor Outer Segment
  • Photoreceptor Inner Segment
  • Membrane
  • Cell Projection
  • Photoreceptor Disc Membrane
  • Cone Photoreceptor Outer Segment
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • Calcium Sensitive Guanylate Cyclase Activator Activity
  • Guanylate Cyclase Regulator Activity
  • Metal Ion Binding
Biological Process
  • Signal Transduction
  • Visual Perception
  • Phototransduction
  • Regulation Of Signal Transduction
  • Positive Regulation Of CGMP-mediated Signaling
  • Positive Regulation Of Guanylate Cyclase Activity
  • Cellular Response To Calcium Ion
Pathways
  • Inactivation, recovery and regulation of the phototransduction cascade
Drugs
  • Myristic acid
Diseases
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
  • Femur bone mineral density x serum urate levels interaction ( 34046847)
  • Spatial processing ( 31596458)
Novel Interacting Genes 10 novel interacting genes: AGR2 BCKDK C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B
Interacting Genes 10 interacting genes: AGR2 BCKDK C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B
Entrez ID 2978
HPRD ID 02648
Ensembl ID ENSG00000048545
Uniprot IDs P43080
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025