SMIM21

Description		small integral membrane protein 21
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Rheumatoid arthritis (ACPA-negative) ( 24532677) Serum uric acid levels in response to allopurinol in gout ( 25676789) Tenofovir clearance in HIV infection ( 26148204)
Novel Interacting Genes		2 novel interacting genes: CFTR DESI1
Interacting Genes		2 interacting genes: CFTR DESI1
Entrez ID		284274
HPRD ID		18769
Ensembl ID		ENSG00000206026
Uniprot IDs		J3KSN8 Q3B7S5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Amelogenesis Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization ATPase-coupled Inorganic Anion Transmembrane Transporter Activity DeSUMOylase Activity Importin-alpha Family Protein Binding Palmitoyl-(protein) Hydrolase Activity Protein Desumoylation Macromolecule Depalmitoylation Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Long-chain Fatty Acyl-CoA Hydrolase Activity Cellular Response To Forskolin Response To Forskolin Protein-containing Complex Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Macromolecule Deacylation Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Protein Export From Nucleus Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking
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