FOXE1

Description		forkhead box E1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Thyroid Hormone Generation Anatomical Structure Morphogenesis Cell Migration Cell Differentiation Thyroid Gland Development Hair Follicle Morphogenesis Positive Regulation Of DNA-templated Transcription Animal Organ Development Thymus Development Embryonic Organ Morphogenesis System Development Roof Of Mouth Development Hard Palate Development Soft Palate Development Chordate Pharynx Development Cranial Skeletal System Development
Pathways
Drugs
Diseases		Bamforth-Lazarus syndrome
GWAS		Alopecia areata ( 25608926) Alzheimer disease and age of onset ( 26830138) Autoimmune thyroid disease ( 32581359) Blond vs. brown/black hair color ( 30531825) Differentiated thyroid cancer ( 28703219) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965 22493691 21981779) Obesity-related traits ( 23251661) Papillary thyroid cancer ( 28703219) Parent of origin effect on language impairment (paternal) ( 24571439) Plasma thyroid-stimulating hormone levels ( 28333968) Serum thyroid-stimulating hormone levels ( 24852370 25436638) Thyroid cancer ( 23894154 25855579 19198613) Thyroid cancer (Papillary, radiation-related) ( 20350937) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335)
Novel Interacting Genes		1 novel interacting genes: PLCB3
Interacting Genes		1 interacting genes: PLCB3
Entrez ID		2304
HPRD ID		04014
Ensembl ID		ENSG00000178919
Uniprot IDs		O00358
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol Phospholipase C Activity Adenylate Cyclase-activating G Protein-coupled CAMP Receptor Signaling Pathway Phospholipase C-activating Serotonin Receptor Signaling Pathway Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Phospholipase C Activity G Protein-coupled Serotonin Receptor Signaling Pathway Molecular Function Activator Activity Phosphatidylinositol-mediated Signaling Postsynaptic Cytosol Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Sequestering Of Calcium Ion Phosphoric Diester Hydrolase Activity Release Of Sequestered Calcium Ion Into Cytosol Calcium Ion Transmembrane Import Into Cytosol Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Phosphatidylinositol Metabolic Process Regulation Of Sequestering Of Calcium Ion Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Calcium Ion Transmembrane Transport Calmodulin Binding Molecular Adaptor Activity Regulation Of Blood Pressure Glycerophospholipid Metabolic Process Lipid Catabolic Process Calcium Ion Transport Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Cadherin Binding Glycerolipid Metabolic Process Phospholipid Metabolic Process
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