ACSL3

Description		acyl-CoA synthetase long chain family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Ligase Activity Protein Kinase Binding Protein Domain Specific Binding Medium-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Palmitoyl-CoA Ligase Activity Fatty Acid-CoA Ligase Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Neuron Differentiation Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Positive Regulation Of Golgi To Plasma Membrane Protein Transport Long-chain Fatty Acid Import Into Cell Positive Regulation Of Secretion Positive Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways		Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Mild influenza (H1N1) infection ( 26379185)
Novel Interacting Genes		9 novel interacting genes: APP BARD1 CAPS MAP2 MMP13 NDRG1 SMARCAL1 TAS2R14 WEE2-AS1
Interacting Genes		9 interacting genes: APP BARD1 CAPS MAP2 MMP13 NDRG1 SMARCAL1 TAS2R14 WEE2-AS1
Entrez ID		2181
HPRD ID		03845
Ensembl ID		ENSG00000123983
Uniprot IDs		O95573
PDB IDs
Enriched GO Terms of Interacting Partners?		Main Axon Acetylcholine Receptor Activator Activity Amyloid-beta Complex Dendritic Shaft Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Lipoprotein Particle Dendrite Development Positive Regulation Of Protein Import Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity Negative Regulation Of MRNA 3'-end Processing BRCA1-BARD1 Complex Dendritic Filopodium Positive Regulation Of Anterograde Synaptic Vesicle Transport Distal Dendrite Apical Distal Dendrite Positive Regulation Of Anterograde Dense Core Granule Transport Primary Dendrite PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Proximal Neuron Projection Dendritic Branch Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Myeloid Leukocyte Activation Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling BRCA1-B Complex Positive Regulation Of Vesicle Transport Along Microtubule Pre-mRNA 5'-splice Site Binding Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Regulation Of Synaptic Vesicle Transport Basal Dendrite Nickel Cation Binding ATP-dependent DNA/DNA Annealing Activity
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