EIF4G2

Description		eukaryotic translation initiation factor 4 gamma 2
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GO Annotations	Cellular Component	Cytosol Adherens Junction Membrane Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	RNA Binding MRNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding
	Biological Process	Translation Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Cell Death Negative Regulation Of Autophagy Positive Regulation Of Cell Growth Regulation Of Cell Cycle
Pathways		ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Novel Interacting Genes		19 novel interacting genes: C1QTNF9 CASP3 CEBPA CREBBP EIF2S2 EIF3A EIF4A1 EIF4A2 EIF4E EIF5 LCOR MKNK1 NCBP1 OGT POLE3 RNF10 SKIL SUMO2 TTC3
Interacting Genes		19 interacting genes: C1QTNF9 CASP3 CEBPA CREBBP EIF2S2 EIF3A EIF4A1 EIF4A2 EIF4E EIF5 LCOR MKNK1 NCBP1 OGT POLE3 RNF10 SKIL SUMO2 TTC3
Entrez ID		1982
HPRD ID		09084
Ensembl ID		ENSG00000110321
Uniprot IDs		P78344 Q2TU89
PDB IDs		3D3M 3L6A 4IUL 9JJ7
Enriched GO Terms of Interacting Partners?		Translational Initiation Translation Initiation Factor Activity Cytoplasmic Translational Initiation Translation RNA Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Macromolecule Metabolic Process Macromolecule Biosynthetic Process Protein Metabolic Process Chromatin DNA Binding Regulation Of Gene Expression Regulation Of Translation Regulation Of Translational Initiation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Protein-RNA Complex Assembly RNA 7-methylguanosine Cap Binding Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Formation Of Cytoplasmic Translation Initiation Complex RNA Binding MRNA Binding Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Translation Factor Activity, RNA Binding Glutamatergic Synapse Negative Regulation Of Biosynthetic Process Histone Acetyltransferase Complex Response To Glucocorticoid Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Organization Response To Corticosteroid Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Pyroptotic Inflammatory Response DNA-binding Transcription Factor Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Negative Regulation Of RNA-dependent RNA Polymerase Activity Eukaryotic Initiation Factor 4G Binding
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