DPAGT1

Description		dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Identical Protein Binding Metal Ion Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective DPAGT1 causes CDG-1j, CMSTA2
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Estimated glomerular filtration rate ( 31152163) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Novel Interacting Genes		7 novel interacting genes: CXCR5 ETS1 LSM8 SLC33A2 THTPA TUBE1 WDR5
Interacting Genes		7 interacting genes: CXCR5 ETS1 LSM8 SLC33A2 THTPA TUBE1 WDR5
Entrez ID		1798
HPRD ID		01879
Ensembl ID		ENSG00000172269
Uniprot IDs		A0A804HI18 A0A804HKZ3 Q9H3H5
PDB IDs		5LEV 5O5E 6BW5 6BW6 6FM9 6FWZ 6JQ3
Enriched GO Terms of Interacting Partners?
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