DIO1

Description		iodothyronine deiodinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Thyroxine 5'-deiodinase Activity Selenium Binding Oxidoreductase Activity Thyroxine 5-deiodinase Activity
	Biological Process	Amino Acid Metabolic Process Thyroid Hormone Generation Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process
Pathways		Regulation of thyroid hormone activity
Drugs
Diseases
GWAS		Free thyroxine concentration ( 25743335) Serum metabolite concentrations in chronic kidney disease ( 33838163) Thyroid hormone levels ( 23408906)
Novel Interacting Genes		2 novel interacting genes: ARTN CD48
Interacting Genes
Entrez ID		1733
HPRD ID		01002
Ensembl ID		ENSG00000211452
Uniprot IDs		A8K415 P49895
PDB IDs
Enriched GO Terms of Interacting Partners?		Glial Cell-derived Neurotrophic Factor Receptor Binding Peyer's Patch Morphogenesis Lymphocyte Migration Into Lymphoid Organs Induction Of Positive Chemotaxis Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Positive Regulation Of Positive Chemotaxis Peripheral Nervous System Development Natural Killer Cell Activation Neuroblast Proliferation Lymphocyte Migration Receptor Tyrosine Kinase Binding
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