SPTSSB

Description		serine palmitoyltransferase small subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Serine Palmitoyltransferase Complex
	Molecular Function	Serine C-palmitoyltransferase Activity Protein Binding
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Endoplasmic Reticulum Organization Sphingolipid Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		IgG1 response to Plasmodium falciparum antigen (GLURP) ( 26741287) Morning person ( 30696823) Number of sexual partners ( 30643258) Parkinson's disease ( 32201043) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Novel Interacting Genes		1 novel interacting genes: DRD3
Interacting Genes		1 interacting genes: DRD3
Entrez ID		165679
HPRD ID		16476
Ensembl ID		ENSG00000196542
Uniprot IDs		Q6ZWB5 Q8NFR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Reflex Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Synaptic Transmission, Glutamatergic G Protein-coupled Receptor Internalization Musculoskeletal Movement, Spinal Reflex Action Synaptic Transmission, Dopaminergic Prepulse Inhibition Behavioral Response To Cocaine Negative Regulation Of Cytosolic Calcium Ion Concentration Response To Histamine Response To Morphine Arachidonate Secretion Musculoskeletal Movement Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Phospholipase C-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Oligodendrocyte Differentiation Dopamine Neurotransmitter Receptor Activity Regulation Of Neurotransmitter Uptake G Protein-coupled Dopamine Receptor Signaling Pathway Regulation Of Dopamine Secretion Negative Regulation Of Glial Cell Differentiation Acid Secretion Dopamine Metabolic Process Response To Cocaine Negative Regulation Of Gliogenesis Regulation Of Catecholamine Secretion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Oligodendrocyte Differentiation Catecholamine Metabolic Process Positive Regulation Of Cytokinesis Negative Regulation Of Synaptic Transmission Negative Regulation Of Blood Pressure Positive Regulation Of Mitotic Nuclear Division Long-chain Fatty Acid Transport Visual Learning Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Social Behavior Visual Behavior Circadian Regulation Of Gene Expression Receptor Internalization Biogenic Amine Metabolic Process Regulation Of Glial Cell Differentiation Negative Regulation Of Protein Secretion Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport
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